Category Archives: Treatment
Mobile phone text messaging interventions for HIV and other chronic diseases: An overview of systematic reviews and framework for evidence transfer
Background Strong international commitment and the widespread use of antiretroviral therapy have led to higher longevity for people living with human immune deficiency virus (HIV). Text messaging interventions have been...
Early versus delayed antiretroviral therapy for HIV and Tuberculosis co-infected patients: A systematic review and meta-analysis of randomized controlled trials
OBJECTIVE: To compare important clinical outcomes between early and delayed initiation of antiretroviral therapy (ART) in adults who had a co-infection of human immunodeficiency virus (HIV) and tuberculosis (TB). METHODS:...
Meta-analysis and time series modeling allow a systematic review of primary HIV-1 drug-resistant prevalence in Latin America and Caribbean.
Here we review the prevalence of HIV-1 primary drug resistance in Latin America and Caribbean using meta-analysis as well as time-series modeling. We also discuss whether there could be a...
Is the atherosclerotic process accentuated under conditions of HIV infection, antiretroviral therapy, and protease inhibitor exposure? Meta-analysis of the markers of arterial structure and function
OBJECTIVE: To evaluate the apparent association of human immunodeficiency virus (HIV) infection, antiretroviral therapy (ART), and protease inhibitor (PI) exposure with the functional and structural markers of vasculature. METHODS: A...
Discussing the effects of poor health literacy on patients facing HIV: A narrative literature review
BACKGROUND: Scholars describe poor health literacy as a “silent epidemic,” which is challenging the functioning of healthcare systems all over the world. Health literacy is mainly meant as an individual...
Housing status, medical care, and health outcomes among people living With HIV/AIDS: A systematic review
BACKGROUND: Accumulating evidence suggests responses to HIV that combine individual-level interventions with those that address structural or contextual factors that influence risks and health outcomes of infection. Housing is such...
Emerging trends of HIV drug resistance in Chinese HIV-infected patients receiving first-line highly active antiretroviral therapy: A systematic review and meta-analysis
BACKGROUND: Highly active antiretroviral therapy (HAART) has led to a dramatic decrease in AIDS-related morbidity and mortality through sustained suppression of human immunodeficiency virus (HIV) replication and reconstitution of the...
A systematic review of a single-class maintenance strategy with nucleoside reverse transcriptase inhibitors in HIV/AIDS
BACKGROUND: Single drug class regimens with nucleotide reverse transcriptase inhibitors (NRTIs) are generally not recommended as initial therapy, because they were inferior compared to therapy with 2 NRTIs plus efavirenz....
Longitudinal and cross sectional assessments of health utility in adults with HIV/AIDS: A systematic review and meta-analysis
BackgroundUtility estimates are important health outcomes for economic evaluation of care and treatment interventions for patients with HIV/AIDS. We conducted a systematic review and meta-analysis of utility measurements to examine...
The meaning and perceived value of mind-body practices for people living with HIV: A qualitative synthesis
Mind-body practices (MBPs) are a subset of complementary medicine that represents a selection of self-care activities that may promote the health of people living with HIV (PLWH). No synthesis of...
Cobicistat: Review of a pharmacokinetic enhancer for HIV infection
PURPOSE: This article reviews the clinical pharmacology, pharmacodynamic and pharmacokinetic (PK) properties, clinical efficacy and tolerability, drug interactions, and dosing and administration of cobicistat. METHODS: Searches of MEDLINE and International...
