Category Archives: Treatment

Optimizing ART adherence: Update for HIV treatment and prevention

2014

Optimal adherence to antiretroviral therapy (ART) is central to achieving viral suppression and positive health outcomes in HIV-infected individuals. Virally suppressed individuals can also reduce the risk of HIV transmission...

Evidence of increased blood pressure and hypertension risk among people living with HIV on antiretroviral therapy: A systematic review with meta-analysis

2016

Owing to antiretroviral drug-induced endothelial dysfunction, HIV-infected patients on antiretroviral therapy (ART) may have elevated blood pressure. We conducted a systematic review and meta-analysis to estimate the effects of ART...

Evidence informing the intersection of HIV, aging and health: A scoping review

2014

The growing number of people over age 50 with HIV requires research, policy, and practice to develop a more comprehensive understanding of the health consequences of HIV in older individuals....

Interventions to improve adherence to antiretroviral therapy: A rapid systematic review

2014

INTRODUCTION: Access to antiretroviral treatment (ART) has substantially improved over the past decade. In this new era of HIV as a chronic disease, the continued success of ART will depend...

The prevalence of HIV drug resistance among treatment-failure individuals and treatment-naive individuals in China: A meta-analysis

2015

OBJECTIVE: To understand drug resistance prevalence among treatment-failure and treatment-naive HIV-positive individuals in China. METHODS: We searched five electronic databases (Wanfang, CNKI, CQVIP, SinoMed, and Pubmed) for studies of HIV...

Predicting treatment failure in adults and children on antiretroviral therapy: A systematic review of the performance characteristics of the 2010 WHO immunologic and clinical criteria for virologic failure

2014

OBJECTIVE: We systematically reviewed the performance of 2010 WHO immunologic and clinical criteria for predicting virologic failure in HIV-infected patients on antiretroviral therapy (ART). DESIGN: Systematic review. METHODS: We used...

A systematic review of the usefulness of statin therapy in HIV-infected patients

2015

HIV-infected patients have a greater prevalence of dyslipidemia, earlier incidence and progression of atherosclerosis, and a nearly twofold increased risk for myocardial infarction compared with those not infected with HIV....

Predictors and correlates of adherence to combination antiretroviral therapy (ART) for chronic HIV infection: A meta-analysis

2014

BACKGROUND: Adherence to combination antiretroviral therapy (ART) is a key predictor of the success of human immunodeficiency virus (HIV) treatment, and is potentially amenable to intervention. Insight into predictors or...

Trends in task shifting in HIV treatment in Africa: Effectiveness, challenges and acceptability to the health professions

2015

BACKGROUND: Task shifting has been suggested to meet the demand for initiating and managing more patients on antiretroviral therapy. Although the idea of task shifting is not new, it acquires...

Economic impact of HIV/AIDS: A systematic review in five European countries

2014

The HIV/AIDS disease represent a priority for all health authorities in all countries and it also represents serious added socioeconomic problems for societies over the world. The aim of this...

Gender difference in advanced HIV disease and late presentation according to European consensus definitions

2015

Effectiveness of highly active antiretroviral therapy is limited for a large proportion of individuals living with HIV presenting for medical care at an advanced stage. Controversial results of gender differences...

Safety and efficacy of lopinavir/ritonavir during pregnancy: A systematic review

2013

The co-formulated, ritonavir-boosted protease inhibitor lopinavir is a frequently used component of HAART for treatment of HIV-infected women during pregnancy and prevention of mother-to-child transmission. We performed a systematic review...

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