Category Archives: Treatment

Discussing the effects of poor health literacy on patients facing HIV: A narrative literature review

2015

BACKGROUND: Scholars describe poor health literacy as a “silent epidemic,” which is challenging the functioning of healthcare systems all over the world. Health literacy is mainly meant as an individual...

Housing status, medical care, and health outcomes among people living With HIV/AIDS: A systematic review

2016

BACKGROUND: Accumulating evidence suggests responses to HIV that combine individual-level interventions with those that address structural or contextual factors that influence risks and health outcomes of infection. Housing is such...

Emerging trends of HIV drug resistance in Chinese HIV-infected patients receiving first-line highly active antiretroviral therapy: A systematic review and meta-analysis

2014

BACKGROUND: Highly active antiretroviral therapy (HAART) has led to a dramatic decrease in AIDS-related morbidity and mortality through sustained suppression of human immunodeficiency virus (HIV) replication and reconstitution of the...

A systematic review of a single-class maintenance strategy with nucleoside reverse transcriptase inhibitors in HIV/AIDS

2014

BACKGROUND: Single drug class regimens with nucleotide reverse transcriptase inhibitors (NRTIs) are generally not recommended as initial therapy, because they were inferior compared to therapy with 2 NRTIs plus efavirenz....

Longitudinal and cross sectional assessments of health utility in adults with HIV/AIDS: A systematic review and meta-analysis

2015

BackgroundUtility estimates are important health outcomes for economic evaluation of care and treatment interventions for patients with HIV/AIDS. We conducted a systematic review and meta-analysis of utility measurements to examine...

The risk of non-melanoma skin cancer in HIV-infected patients: New data and meta-analysis

2015

BACKGROUND: The role of HIV/AIDS in non-melanoma skin cancer is not well defined. OBJECTIVES: We sought to update the evidence of the association between HIV/AIDS and risk of non-melanoma skin...

Meta-analysis and time series modeling allow a systematic review of primary HIV-1 drug-resistant prevalence in Latin America and Caribbean.

2015

Here we review the prevalence of HIV-1 primary drug resistance in Latin America and Caribbean using meta-analysis as well as time-series modeling. We also discuss whether there could be a...

Is the atherosclerotic process accentuated under conditions of HIV infection, antiretroviral therapy, and protease inhibitor exposure? Meta-analysis of the markers of arterial structure and function

2015

OBJECTIVE: To evaluate the apparent association of human immunodeficiency virus (HIV) infection, antiretroviral therapy (ART), and protease inhibitor (PI) exposure with the functional and structural markers of vasculature. METHODS: A...

Paradoxical TB-IRIS in HIV-infected adults: A systematic review and meta-analysis

2015

Paradoxical tuberculosis immune reconstitution inflammatory syndrome (TB-IRIS) was first described almost two decades ago. We undertook this systematic review and meta-analysis to collate findings across studies that have reported the...

Isoniazid prophylactic therapy for the prevention of tuberculosis in HIV infected adults: A systematic review and meta-analysis of randomized trials

2015

BACKGROUND: Infection with Human Immunodeficiency virus (HIV) is an important risk factor for Tuberculosis (TB). Anti-Retroviral Therapy (ART) has improved the prognosis of HIV and reduced the risk of TB...

Equity in utilization of antiretroviral therapy for HIV-infected people in South Africa: A systematic review

2014

INTRODUCTION: About half a million people in South Africa are deprived of antiretroviral therapy (ART), and there is little systematic knowledge on who they are – e.g. by severity of...

Systematic review of HIV drug resistance in Southeast Asia

2013

In 2010, 3.5 million people were living with HIV in the World Health Organization Southeast Asia Region (SEAR), giving this region the greatest burden of HIV after Africa. Scale-up of...

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