Category Archives: Treatment

Antiretroviral therapy in prevention of HIV and TB: Update on current research efforts

2011

There is considerable scientific evidence supporting the use of antiretroviral therapy (ART) in prevention of human immunodeficiency virus (HIV) and tuberculosis (TB) infections. The complex nature of the HIV and...

Fosamprenavir: A review of its use in the management of antiretroviral therapy-naive patients with HIV infection

2004

Fosamprenavir (GW433908, Lexiva, Telzir) is an oral prodrug of the protease inhibitor (PI) amprenavir, with a reduced daily pill burden. Fosamprenavir, in combination with other antiretroviral agents, is indicated for...

Antiretroviral drug resistance testing in patients with HIV-1 infection: A meta-analysis study

2002

Background: HIV-1 resistance tests, both phenotype and genotype, have been entering clinical practice during the last years, but limited prospective studies have been reported in antiretroviral-treated patients with virological failure....

Family-centred approaches to the prevention of mother to child transmission of HIV

2010

Prevention of mother to child transmission (PMTCT) programmes have traditionally been narrow in scope, targeting biomedical interventions during the perinatal period, rather than considering HIV as a family disease. This...

Group psychotherapies for depression in persons with HIV: A systematic review

2013

Studies investigating effectiveness of group psychotherapy intervention in depression in persons with HIV have showed varying results with differing effect sizes. A systematic review of randomized controlled trials of group...

Role of therapeutic drug monitoring for protease inhibitors

2001

OBJECTIVE: To review the role of therapeutic drug monitoring (TDM) for protease inhibitors in the treatment of HIV infection. DATA SOURCES: Primary articles were identified using MEDLINE (1966-October 2000), EMBASE...

Effect of cotrimoxazole on mortality in HIV-infected adults on antiretroviral therapy: A systematic review and meta-analysis

2012

OBJECTIVE: To determine whether cotrimoxazole reduces mortality in adults receiving antiretroviral therapy (ART) for human immunodeficiency virus (HIV) infection in low- and middle-income countries through a systematic review and meta-analysis....

Protease inhibitors and avascular necrosis: A systematic review and meta-analysis

2014

Avascular necrosis (AVN) is a pathological process associated with many medical conditions, including human immunodeficiency virus (HIV) infection. Whether or not the use of protease inhibitors (PIs) confers additional risk...

The intersection of intimate partner violence and HIV in U.S. women: A review

2014

The purposes of this study were to (a) review original research in the United States on the intersection of HIV risk and intimate partner violence (IPV) in women, and (b)...

Protease inhibitor-associated QT interval prolongation

2011

OBJECTIVE: To evaluate the literature on protease inhibitor (PI)-associated QT interval prolongation and risk for torsade de pointes in patients infected by HIV. DATA SOURCES: Primary literature was identified through...

Alcohol and sexual risk reduction interventions among people living in Russia: A systematic review and meta-analysis

2014

Russia has one of the highest rates of alcohol consumption and is experiencing one of the fastest-growing HIV epidemics in the world. Given these co-occurring health problems, we systematically reviewed...

Cannabinoids for treatment of chronic non-cancer pain: A systematic review of randomized trials

2011

Effective therapeutic options for patients living with chronic pain are limited. The pain relieving effect of cannabinoids remains unclear. A systematic review of randomized controlled trials (RCTs) examining cannabinoids in...

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