Category Archives: Treatment
Barriers to and enablers of adherence to the treatment of active drug-sensitive tuberculosis in people living with HIV: A mixed method systematic review
BACKGROUND: Adherence to tuberculosis (TB) treatment is essential in improving treatment outcomes and reducing TB-related mortality. People living with HIV (PLWH) are at a higher risk of developing and dying...
Incidence of loss to follow-up among East African adults on antiretroviral therapy: A systematic review and meta-analysis
Background Individuals with human immunodeficiency virus receive antiretroviral treatment regardless of their clinical stage or CD4 count. While the “Universal Test and Treat” approach offers benefits, loss to follow-up remains...
HIV pre-exposure prophylaxis among people with criminal justice involvement in the United States: A systematic review
People with criminal justice involvement (PCJI) face a heightened risk of HIV yet remain underserved by prevention strategies such as pre-exposure prophylaxis (PrEP). This systematic review synthesizes current evidence on...
The reasons of late diagnosis in patients with HIV/AIDS: A meta-synthesis
PURPOSE: To comprehensively integrate qualitative findings on the reasons of late diagnosis in HIV/AIDS patients and to encourage timely clinic consultations for advisory purposes. METHODS: A qualitative systematic review utilizing...
Human milk oligosaccharides, microbiome, antiretroviral therapy and HIV infected mothers: Reasons to still promote breastfeeding in HIV context of lactating countries, a mini-narrative review
Breastfeeding is the preferred feeding for newborns during the first 6 months of life and until the age of 2 years or beyond. The benefits of breastfeeding remain significant, even in cases...
The association between different levels of suppressed viral load and the risk of sexual transmission of HIV among serodiscordant couples on antiretroviral therapy: A systematic review
The risk of sexual transmission of HIV in serodiscordant couples when the partner living with HIV (PLHIV) uses antiretroviral therapy (ART) and maintains a suppressed viral load (VL) (< 200...
Global prevalence of HIV and Mycobacterium tuberculosis co-infection: A systematic review and meta-analysis of 371 included articles
OBJECTIVES: Tuberculosis and Human Immunodeficiency Virus (HIV) are two diseases that have imposed the heaviest burden globally. This study aims to determine the global prevalence of Mycobacterium tuberculosis and HIV...
Lessons from the field: A systematic review of global and continental prevalence and challenges of people living with HIV (COVID-19)
COVID-19, caused by SARS-CoV-2, accounts for 186 million infections and more than 4 million deaths globally. This systematic review concentrates on the epidemiological profiling of HIV/AIDS, along with the unique...
Factors influencing antiretroviral therapy adherence among youth living with HIV: A systematic review and meta-analysis
Background Adherence to antiretroviral therapy (ART) is vital for controlling the viral load and disease progression in people living with HIV. Previous reviews on ART adherence among youths living with...
Association between HIV infection and type 2 diabetes mellitus: Global incidence, prevalence, and risk factors—A systematic review and meta-analysis
Introduction People living with HIV (PLHIV) are at an increased risk of type 2 diabetes mellitus (T2DM) due to aging, lifestyle, and antiretroviral therapy-related factors. This systematic review and meta-analysis...
Contextual and culturally adapted interventions to improve HIV outcomes: A scoping review
BACKGROUND: Antiretroviral therapy is widely available, yet structural, social, and cultural barriers still limit human immunodeficiency virus prevention and care. Prevention tools such as consistent condom use and pre-exposure prophylaxis...
