Category Archives: Treatment

A systematic review of the effects of exercise interventions on body composition in HIV+ adults

2015

Over the years, physical activity and exercise have been used to positively impact the health and quality of life of persons infected with HIV and, more recently, has been associated...

Initial highly-active antiretroviral therapy with a protease inhibitor versus a non-nucleoside reverse transcriptase inhibitor: Discrepancies between direct and indirect meta-analyses

2006

BACKGROUND: The optimum treatment choice between initial highly-active antiretroviral therapy (HAART) with a protease inhibitor (PI) versus a non-nucleoside reverse transcriptase inhibitor (NNRTI) is uncertain. An indirect analysis reported that...

Estimating per-act HIV transmission risk: A systematic review

2014

BACKGROUND: Effective HIV prevention programs rely on accurate estimates of the per-act risk of HIV acquisition from sexual and parenteral exposures. We updated the previous risk estimates of HIV acquisition...

Does HIV infection have an impact upon dental implant osseointegration? A systematic review

2015

Objective: A systematic review is made to determine whether human immunodeficiency virus (HIV) infection has an impact upon dental implant osseointegration. Study Design: A PubMed (MEDLINE) literature search was made...

Electronic medication monitoring-informed counseling to improve adherence to combination anti-retroviral therapy and virologic treatment outcomes: A meta-analysis

2015

BACKGROUND: Adherence to combination anti-retroviral therapy for HIV infection is a primary determinant of treatment success, but is often suboptimal. Previous studies have suggested that electronic medication monitoring-informed counseling is...

Pharmaceutical interventions in antiretroviral therapy: Systematic review and meta-analysis of randomized clinical trials

2015

WHAT IS KNOWN AND OBJECTIVE: High levels of adherence to antiretroviral therapy (ART) are needed to achieve the desired results. Because pharmaceutical care might contribute to improved adherence to treatment,...

A systematic review of the inclusion (or exclusion) of women in HIV research: From clinical studies of antiretrovirals and vaccines to cure strategies

2016

INTRODUCTION: The effect of clinical interventions can differ due to sex/gender. Studies have shown that women are often underrepresented in medical research. The aim of this systematic literature review was...

Antiretroviral regimens for patients with HIV who fail first-line antiretroviral therapy

2007

BACKGROUND: Highly active antiretroviral therapy has reduced the morbidity and mortality of patients with HIV/AIDS. A common first-line ART regimen includes a non-nucleoside reverse transcriptase inhibitor (NNRTI) and two nucleoside...

Treatment of active tuberculosis in HIV-coinfected patients: A systematic review and meta-analysis.

2010

Rationale: Patients with HIV-related tuberculosis (TB) have an increased risk of death, TB treatment failure, and relapse. There are several areas of uncertainty regarding the treatment of active TB in...

Complementary therapies for the treatment of HIV: In search of the evidence

2005

The use of complementary and alternative medicine (CAM) is widespread. Yet, little is known about the evidence supporting its use in HIV/AIDS. We conducted a systematic review of randomized clinical...

Epidemiology of HIV-related neuropathy: A systematic literature review

2012

We sought to identify and summarize the incidence and prevalence of neuropathy among HIV patients and subgroups. A systematic search of the literature was performed using MEDLINE and EMBASE. The...

Meta-analysis of randomized controlled trials of simplified versus continued protease inhibitor-based antiretroviral therapy in HIV-1-infected patients

2003

Objective: To evaluate the efficacy and safety of simplified maintenance therapy (SMT) compared with continued protease inhibitor (PI) therapy. Design: Meta-analysis of nine randomized controlled trials in which 833 patients...

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