Category Archives: Treatment
Efficacy of antiretroviral therapy adherence interventions: A research synthesis of trials, 1996 to 2004
OBJECTIVE: To conduct a quantitative review of published trials of antiretroviral therapy (ART) adherence interventions. DESIGN: A research synthesis of published ART adherence intervention outcome studies. SAMPLE: ART adherence intervention...
Prevalence of resistance to nevirapine in mothers and children after single-dose exposure to prevent vertical transmission of HIV-1: A meta-analysis
BACKGROUND: Single-dose nevirapine (NVP) is the main option for the prevention of mother-to-child transmission (PMTCT) of HIV-1 in countries with limited resources. However, the use of single-dose NVP results in...
Liver transplant outcomes in HIV-infected patients: A systematic review and meta-analysis with synthetic cohort
OBJECTIVES: : The relative success of liver transplantation in those with HIV compared to HIV-uninfected individuals remains a point of intense debate. We aimed to evaluate the effectiveness of liver...
Cost-effectiveness of adherence interventions for highly active antiretroviral therapy: A systematic review
Objectives: The objective of this systematic review was to evaluate the cost-effectiveness of interventions aiming to increase the adherence to highly active antiretroviral therapy (HAART) in HIV-infected patients in developed...
Selenium supplementation in HIV-infected patients: Is there any potential clinical benefit?
In HIV-infected patients undergoing antiretroviral therapy, the question of whether selenium supplementation has any therapeutic benefit is still open. With recent popular coverage of this issue, many patients have considered...
Does highly active antiretroviral therapy improve neurocognitive function? A systematic review
Highly active antiretroviral therapy (HAART) reduces the incidence of human immunodeficiency virus (HIV) dementia (HAD), whereas the overall prevalence appears to have increased. Recent changes to diagnostic nosology have emphasized...
Switching from suppressive protease inhibitor-based regimens to nevirapine-based regimens: A meta-analysis of randomized controlled trials
OBJECTIVES: We performed a meta-analysis to assess the efficacy and safety of switching from protease inhibitor (PI)- to nevirapine (NVP)-based regimens in HIV-infected patients in whom virological suppression had been...
Co-formulated abacavir-lamivudine-zidovudine for initial treatment of HIV infection and AIDS
Background: UNAIDS estimates that 34 million people are currently living with the human immunodeficiency virus (HIV) worldwide. Currently recommended regimens for initiating HIV treatment consist of either a non-nucleoside reverse...