Category Archives: Treatment
Systematic review of combination antiretroviral therapy with didanosine plus hydroxyurea: A partial solution to Africa’s HIV/AIDS problem?
Effective antiretroviral therapy remains beyond the reach of most human immunodeficiency virus (HIV)-infected persons living in the third world because of its tremendous cost. The cancer drug, hydroxyurea, inhibits HIV-1...
Children who acquire HIV infection perinatally are at higher risk of early death than those acquiring infection through breastmilk: A meta-analysis
BACKGROUND: Assumptions about survival of HIV-infected children in Africa without antiretroviral therapy need to be updated to inform ongoing UNAIDS modelling of paediatric HIV epidemics among children. Improved estimates of...
HIV, alcohol dependence, and the criminal justice system: A review and call for evidence-based treatment for released prisoners
BACKGROUND: People with both HIV and alcohol use disorders (AUDs) are disproportionately concentrated within the U.S. criminal justice system; approximately one-quarter of all people with HIV cycle through the system...
Etravirine as a switching option for patients with HIV RNA suppression: A review of recent trials
Unlike other nonnucleoside reverse transcriptase inhibitors, etravirine is only approved for use in treatment-experienced patients. In the DUET 1 and 2 trials, 1203 highly treatment-experienced patients were randomized to etravirine...
Sex differences in HIV outcomes in the highly active antiretroviral therapy era: A systematic review.
Objective: To assess sex disparities in AIDS clinical and laboratory outcomes in the HAART era. Design: Systematic review of published literature on mortality, disease progression, and laboratory outcomes among persons...
Mobile phone text messaging for promoting adherence to antiretroviral therapy in patients with HIV infection
BACKGROUND: More than 34 million people are presently living with HIV infection. Antiretroviral therapy (ART) can help these people to live longer, healthier lives, but adherence to ART can be...
A systematic review of effects of concurrent strength and endurance training on the health-related quality of life and cardiopulmonary status in patients with HIV/AIDS
PURPOSE: To determine the effects of concurrent strength and endurance training (concurrent training) on the Health-Related Quality of Life (HRQOL) and cardiopulmonary status among HIV-infected patients, using a systematic search...
Integrating antiretroviral therapy into antenatal care and maternal and child health settings: a systematic review and meta-analysis
OBJECTIVE: To determine whether integrating antiretroviral therapy (ART) into antenatal care (ANC) and maternal and child health (MCH) clinics could improve programmatic and patient outcomes. METHODS: The authors systematically searched...
Analysis of neuropsychiatric adverse events during clinical trials of efavirenz in antiretroviral-naive patients: A systematic review
People with HIV infection have several risk factors for developing neuropsychiatric adverse events: preexisting conditions, HIV disease stage, and antiretroviral treatment. The most widely used system for assessing neuropsychiatric adverse...
