Category Archives: Treatment
Depression, alcohol use and adherence to antiretroviral therapy in sub-saharan Africa: A systematic review
This study evaluated estimates of depression symptoms, major depression, alcohol use or disorders and their association with ART adherence in sub-Saharan Africa. Studies published between January 1, 2006 and July...
Impact of antiretroviral drugs in pregnant women and their children in Africa: HIV resistance and treatment outcomes
The global community has committed itself to eliminating new pediatric HIV infections by 2015 and improving maternal, newborn, and child health and survival in the context of HIV. Such objectives...
What is the relevance of mental health to HIV/AIDS care and treatment programs in developing countries? A systematic review
The expansion of AIDS treatment initiatives in resource-poor settings provides an opportunity for integrating mental health care into these programs. This systematic review of the literature on HIV and mental...
Evaluating HIV/AIDS disparities for blacks in the United States: A review of antiretroviral and mortality studies
The purpose of this systematic review was to identify studies that evaluated HIV/AIDS disparities by examining differences in the receipt of antiretroviral therapy and differences in mortality between blacks and...
Quantifying and addressing losses along the continuum of care for people living with HIV infection in sub-Saharan Africa: A systematic review
INTRODUCTION: Recent years have seen an increasing recognition of the need to improve access and retention in care for people living with HIV/AIDS. This review aims to quantify patients along...
Effects of nucleoside reverse transcriptase inhibitor backbone on the efficacy of first-line boosted highly active antiretroviral therapy based on protease inhibitors: Meta-regression analysis of 12 clinical trials in 5168 patients
Objectives: Tenofovir/emtricitabine (TDF/FTC) and abacavir/lamivudine (ABC/3TC) are widely used with ritonavir (RTV)-boosted protease inhibitors (PIs) as first-line highly active antiretroviral therapy (HAART), but there is conflicting evidence on their relative...
Virological follow-up of adult patients in antiretroviral treatment programmes in sub-Saharan Africa: A systematic review
Following large-scale roll-out of antiretroviral therapy in sub-Saharan Africa, the non-clinical efficacy of antiretroviral therapy has received little attention. We aimed to systematically review virological efficacy and drug-resistance outcomes of...
Risk of resistance to highly active antiretroviral therapy among HIV-positive injecting drug users: A meta-analysis
Although highly active antiretroviral therapy (HAART) is an effective treatment for HIV, many physicians withhold this treatment from HIV-positive injecting drug users (IDUs) because of fears of non-adherence and consequent...
