Category Archives: Treatment

The association of hospital, clinic and provider volume with HIV/AIDS care and mortality: Systematic review and meta-analysis

2012

The objective of this systematic review and meta-analysis is to examine the association between hospital, clinic and provider patient volumes on HIV/AIDS patient outcomes including mortality, antiretroviral (ARV) use and...

Workplace programmes for HIV and tuberculosis: A systematic review to support development of international guidelines for the health workforce

2013

The health service sector has a vital role to play in delivering human immunodeficiency virus (HIV) and tuberculosis (TB) prevention, treatment and care, yet evidence indicates that healthcare workers (HCWs)...

Acceptability of HIV self-testing: A systematic literature review

2013

BACKGROUND: The uptake of HIV testing and counselling services remains low in risk groups around the world. Fear of stigmatisation, discrimination and breach of confidentiality results in low service usage...

Minimizing resistance consequences after virologic failure on initial combination therapy: A systematic overview

2006

OBJECTIVE: To identify optimal first-line therapies based on the rate of virologic success (VS) and the preservation of future treatment options in antiretroviral therapy (ART)-naive subjects. DESIGN: Systematic overview of...

Global trends in antiretroviral resistance in treatment-naive individuals with HIV after rollout of antiretroviral treatment in resource-limited settings: A global collaborative study and meta-regression analysis

2012

BACKGROUND: The emergence and spread of high levels of HIV-1 drug resistance in resource-limited settings where combination antiretroviral treatment has been scaled up could compromise the effectiveness of national HIV...

Socioeconomic factors in adherence to HIV therapy in low- and middle-income countries

2013

It is not clear what effect socioeconomic factors have on adherence to antiretroviral therapy (ART) among patients in low- and middle-income countries. We performed a systematic review of the association...

Depression and HIV/AIDS treatment nonadherence: A review and meta-analysis

2011

We meta-analyzed the relationship between depression and HIV medication nonadherence to calculate the overall effect size and examine potential moderators. Overall, across 95 independent samples, depression was significantly (P <...

Treatment-related optimistic beliefs and risk of HIV transmission: A review of recent findings (2009-2012) in an era of treatment as prevention

2013

The promising outlook for HIV treatment as prevention (TasP) offered by the recent success in clinical trials has highlighted the need for effort against over-optimism toward anti-retroviral therapy (ART). It...

A meta-analysis of six placebo-controlled trials of thiazolidinedione therapy for HIV lipoatrophy

2010

Objective: To determine the impact of thiazolidinediones (TZD) on changes in limb fat mass in HIV-infected individuals, particularly in those not receiving a thymidine analogue.Methods: Individual patient data from placebo-controlled,...

A review of anti-D treatment of childhood idiopathic thrombocytopenic purpura

2006

Treatment of childhood idiopathic thrombocytopenic purpura is still an area of controversy. We reviewed the literature on anti-D treatment. Most studies used intravenous anti-D. Single doses of 50 microg/kg increased...

Yield of HIV-associated tuberculosis during intensified case finding in resource-limited settings: A systematic review and meta-analysis

2010

Intensified case finding is the regular screening for evidence of tuberculosis in people infected with HIV, at high risk of HIV, or living in congregate settings. We systematically reviewed studies...

Evidence behind the WHO guidelines: Hospital Care for Children: What is the aetiology and treatment of chronic diarrhoea in children with HIV?

2009

The World Health Organization has produced guidelines for the management of common illnesses in hospitals with limited resources. This series reviews the scientific evidence behind WHO’s recommendations. The WHO guidelines,...

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