Category Archives: Treatment
Telephone delivered interventions for reducing morbidity and mortality in people with HIV infection
Background: This is one of three Cochrane reviews examining the role of the telephone in HIV/AIDS services. Telephone interventions, delivered either by landline or mobile phone, may be useful in...
Efficacy and tolerability of initial antiretroviral therapy: A systematic review
OBJECTIVES: Successful antiretroviral therapy (ART) is largely attributed to the type of third drug. Guidelines recommend regimens without systematic review of all factors that might affect treatment success, such as...
The impact of African Americans’ beliefs about HIV medical care on treatment adherence: A systematic review and recommendations for interventions.
Disparities in access to and retention of regular HIV medical treatment persist among African Americans living with HIV. Many scholars believe that the mistrust of health care held by many...
Home-based care for reducing morbidity and mortality in people infected with HIV/AIDS
BACKGROUND: Home-based care (HBC), to promote quality-of-life and limit hospital care, is used in many countries, especially where public health services are overburdened. OBJECTIVES: This review assessed the effects of...
Stigma in the HIV/AIDS epidemic: A review of the literature and recommendations for the way forward
Although stigma is considered a major barrier to effective responses to the HIV/AIDS epidemic, stigma reduction efforts are relegated to the bottom of AIDS programme priorities. The complexity of HIV/AIDS-related...
The impact of HIV treatment on risk behaviour in developing countries: A systematic review
In developing countries, access to antiretroviral therapy (ART) is improving as HIV treatment becomes a greater priority in the global fight against AIDS. While ART has clearly beneficial clinical effects,...
Non-injection drug use and HIV disease progression in the era of combination antiretroviral therapy
Little is known about the effects of non-injection drug use (NIDU) on HIV antiretroviral treatment outcomes. We conducted a systematic literature search and identified nine publications from prospective cohort studies...
Vitamin supplementation for prevention of mother-to-child transmission of HIV and pre-term delivery: A systematic review of randomized trial including more than 2800 women
Background: Observational studies have suggested that low serum vitamin levels are associated with increased mother-to-child transmission (MTCT) of HIV and increased preterm delivery. We aimed to determine the efficacy of...
Antiretroviral therapy in prevention of HIV and TB: Update on current research efforts
There is considerable scientific evidence supporting the use of antiretroviral therapy (ART) in prevention of human immunodeficiency virus (HIV) and tuberculosis (TB) infections. The complex nature of the HIV and...
Fosamprenavir: A review of its use in the management of antiretroviral therapy-naive patients with HIV infection
Fosamprenavir (GW433908, Lexiva, Telzir) is an oral prodrug of the protease inhibitor (PI) amprenavir, with a reduced daily pill burden. Fosamprenavir, in combination with other antiretroviral agents, is indicated for...
Antiretroviral drug resistance testing in patients with HIV-1 infection: A meta-analysis study
Background: HIV-1 resistance tests, both phenotype and genotype, have been entering clinical practice during the last years, but limited prospective studies have been reported in antiretroviral-treated patients with virological failure....
