Category Archives: Treatment
Alcohol and sexual risk reduction interventions among people living in Russia: A systematic review and meta-analysis
Russia has one of the highest rates of alcohol consumption and is experiencing one of the fastest-growing HIV epidemics in the world. Given these co-occurring health problems, we systematically reviewed...
Cannabinoids for treatment of chronic non-cancer pain: A systematic review of randomized trials
Effective therapeutic options for patients living with chronic pain are limited. The pain relieving effect of cannabinoids remains unclear. A systematic review of randomized controlled trials (RCTs) examining cannabinoids in...
Treatment of helminth co-infection in individuals with HIV-1: A systematic review of the literature
BACKGROUND AND OBJECTIVES: The HIV-1 pandemic has disproportionately affected individuals in resource-constrained settings. It is important to determine if other prevalent infections affect the progression of HIV-1 in co-infected individuals...
Does increased hepatitis B vaccination dose lead to a better immune response in HIV-infected patients than standard dose vaccination: A meta-analysis?
Human immunodeficiency virus (HIV)-infected patients often fail to produce protective antibodies to hepatitis B virus (HBV) vaccine. Some reports have suggested that increased-dose vaccination improves immune response to HBV vaccine...
Non-physician clinician provided HIV treatment results in equivalent outcomes as physician-provided care: A meta-analysis
INTRODUCTION: A severe healthcare worker shortage in sub-Saharan Africa is inhibiting the expansion of HIV treatment. Task shifting, the transfer of antiretroviral therapy (ART) management and initiation from doctors to...
No association of abacavir use with myocardial infarction: Findings of an FDA meta-analysis
BACKGROUND: Several studies have reported an association between abacavir (ABC) exposure and increased risk of myocardial infarction (MI) among HIV-infected individuals. Randomized controlled trials (RCTs) and a pooled analysis by...
Antiretroviral effects on HIV-1 RNA, CD4 cell count and progression to AIDS or death: A meta-regression analysis
OBJECTIVE: Governments, clinicians and drug-licensing bodies have adopted changes in CD4 cell counts and HIV-1 RNA levels as evidence of effectiveness for new therapeutic interventions. We aimed to determine the...
Immune reconstitution inflammatory syndrome associated with Mycobacterium tuberculosis infection: A systematic review
HIV and tuberculosis (TB) are leading global causes of mortality and morbidity. Highly active antiretroviral therapy (HAART) is often initiated in patients being treated for TB. The immune recovery associated...
