Category Archives: Treatment
Association of HIV and ART with cardiometabolic traits in sub-Saharan Africa: A systematic review and meta-analysis
BACKGROUND: Sub-Saharan Africa (SSA) has the highest burden of HIV in the world and a rising prevalence of cardiometabolic disease; however, the interrelationship between HIV, antiretroviral therapy (ART) and cardiometabolic...
Costs and efficiency of integrating HIV/AIDS services with other health services: A systematic review of evidence and experience
OBJECTIVES: To review the literature on the potential efficiency gains of integrating HIV services with other health services. DESIGN: Systematic literature review. Search of electronic databases, manual searching and snowball...
Task shifting for the delivery of pediatric antiretroviral treatment: A systematic review
BACKGROUND: Pediatric antiretroviral treatment coverage in resource-limited settings continues to lag behind adults. Task shifting is an effective approach broadly used for adults, which some countries have also adopted for...
Association between vitamin D and hepatitis C virus infection: A meta-analysis
AIM: To evaluate the association between 25-hydroxyvitamin D [25(OH)D] and sustained virological response (SVR) in hepatitis C virus (HCV) infected individuals. METHODS: Relevant studies were identified by systematically searching MEDLINE...
Antiretroviral regimens for patients with HIV who fail first-line antiretroviral therapy
BACKGROUND: Highly active antiretroviral therapy has reduced the morbidity and mortality of patients with HIV/AIDS. A common first-line ART regimen in low-resource settings includes a non-nucleoside reverse transcriptase inhibitor (NNRTI)...
Cognitive-behavioural interventions for mood and anxiety disorders in HIV: A systematic review
BACKGROUND: Mood and anxiety disorders are highly prevalent and comorbid with HIV/AIDS. However, there is a paucity of research on the effectiveness of cognitive-behavioural interventions (CBI) for common mental disorders...
Association of genital human papillomavirus infection with HIV acquisition: A systematic review and meta-analysis
OBJECTIVES: To conduct a systematic review and a meta-analysis of epidemiological studies investigating the association of genital human papillomavirus (HPV) infection and HIV acquisition. DESIGN: Systematic review and meta-analysis. DATA...
Does epoetin alfa improve health-related quality of life in chronically ill patients with anemia: Summary of trials of cancer, HIV/AIDS, and chronic kidney disease
OBJECTIVES: Anemia, defined as having low levels of hemoglobin (HGB), is caused by disease-related (e.g., bone marrow suppression, nutritional deficiency) or treatment-related (e.g., chemotherapy, antiretroviral therapy) factors. Although epoetin alfa...
Does antiretroviral therapy improve HIV-associated cognitive impairment? A quantitative review of the literature
The development of antiretroviral therapy (ART) has dramatically improved survival for those living with human immunodeficiency virus (HIV), but whether ART improves cognitive functioning remains unclear. The aim of the...
Non-physician clinician provided HIV treatment results in equivalent outcomes as physician-provided care: A meta-analysis
INTRODUCTION: A severe healthcare worker shortage in sub-Saharan Africa is inhibiting the expansion of HIV treatment. Task shifting, the transfer of antiretroviral therapy (ART) management and initiation from doctors to...
