Category Archives: Treatment

Lessons learned from use of highly active antiretroviral therapy in Africa

2005

BACKGROUND: Because antiretrovirals are becoming increasingly available in developing countries, we reviewed the findings of studies that have documented highly active antiretroviral therapy (HAART) use in Africa to identify lessons...

A critical evaluation of the therapeutic range of indinavir

2002

OBJECTIVE: To provide a summary of the patient population, study characteristics, and important findings of the key studies in the literature evaluating concentration-effect relationships and the therapeutic range for indinavir....

Treatment outcomes of patients on second-line antiretroviral therapy in resource-limited settings: A systematic review and meta-analysis

2012

Background: A growing proportion of patients on antiretroviral therapy in resource-limited settings have switched to second-line regimens. We carried out a systematic review in order to summarize reported rates and...

Persistent difficulties in switching to second-line ART in sub-saharan Africa — A systematic review and meta-analysis

2013

OBJECTIVES: Switching to second-line antiretroviral therapy (ART) largely depends on careful clinical assessment and access to biological measurements. We performed a systematic review and meta-analysis to estimate the incidence of...

Immediate versus deferred zidovudine (AZT) in asymptomatic or mildly symptomatic HIV infected adults

2002

BACKGROUND: Zidovudine (AZT) monotherapy was the first antiretroviral drug to be tested widely. Subsequent trials in asymptomatic or early symptomatic HIV infection indicated short-term delays in disease progression with AZT,...

Antidepressants for neuropathic pain

2007

Background: This is an updated version of the original Cochrane review published in Issue 3, 2005 of The Cochrane Library . For many years antidepressant drugs have been used to...

Cardiac biomarkers in persons with HIV infection: A review of the literature

2014

No abstract.

Immunological and virological benefits resulted from short-course treatment during primary HIV infection: A meta-analysis

2013

OBJECTIVES: To assess the potential immunological and virological effects that result from short-course antiretroviral treatment during primary HIV infection (PHI). And to investigate whether treatment initiation time, treatment duration and...

Trichomoniasis and HIV interactions: A review

2013

OBJECTIVE: To discuss the epidemiology of Trichomonas vaginalis (TV) and HIV co-infections, the role of TV in acquisition and transmission of HIV, special treatment considerations for TV among women with...

Smoking-cessation interventions in people living with HIV infection: A systematic review

2013

Tobacco smoking remains a prevalent behavior in people living with HIV infection (PLWHs) and is associated with impaired immune functioning, increased cardiovascular risk, and decreased response to antiretroviral therapy. This...

The impact of participation in performing arts on adolescent health and behaviour: A systematic review of the literature

2008

This article reports a systematic review of literature published between 1994 and 2004 on the effects of performing arts for health in young people aged 11-18. The review includes research...

Unit costs for delivery of antiretroviral treatment and prevention of mother-to-child transmission of HIV: A systematic review for low- and middle-income countries

2011

As antiretroviral treatment (ART) for HIV/AIDS is scaled up globally, information on per-person costs is critical to improve efficiency in service delivery and to maximize coverage and health impact. The...

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