Category Archives: Treatment

Interventions to improve adherence to antiretroviral therapy in children with HIV infection

2011

BACKGROUND: Achieving and maintaining high levels of medication adherence are required to achieve the full benefits of antiretroviral therapy (ART), yet suboptimal adherence among children is common in both developed...

Effectiveness of antiretroviral therapy in HIV-infected children under 2 years of age

2012

BACKGROUND: In the absence of antiretroviral therapy (ART), over 50% of HIV-infected infants progress to AIDS and death by 2 years of age. However, there are challenges to initiate ART...

Screening for human immunodeficiency virus in pregnant women: Evidence synthesis

2005

Context: An estimated 6,000 to 7,000 HIV-infected women give birth each year in the United States. Although the number of cases of perinatally acquired HIV infection has declined sharply in...

Treatment outcomes of treatment-naive Hepatitis C patients co-infected with HIV: A systematic review and meta-analysis of observational cohorts

2013

INTRODUCTION: Co-infection with Hepatitis C (HCV) and HIV is common and HIV accelerates hepatic disease progression due to HCV. However, access to HCV treatment is limited and success rates are...

Effects of physical tracing on estimates of loss to follow-up, mortality and retention in low aetroviral therapnd middle income country antiry programs: A systematic review

2013

BACKGROUND: A large proportion of patients receiving antiretroviral therapy (ART) in low and middle income countries (LMICs) have unknown treatment outcomes and are classified as lost to follow-up (LTFU). Physical...

The impact of HIV treatment as prevention in the presence of other prevention strategies: Lessons learned from a review of mathematical models set in resource-rich countries

2013

OBJECTIVE: We aimed to assess the potential prevention benefits of HIV treatment as prevention (TasP) in resource-rich countries and examine the potential interactions between TasP and other prevention strategies by...

Meta-analysis of prevention and treatment of toxoplasmic encephalitis in HIV-infected patients

2013

Toxoplasmic encephalitis (TE) is one of the most common central nervous system (CNS) opportunistic infections in HIV-infected patients. It can be prevented and treated through drug regimen. However, drugs have...

A systematic review of behavioral and treatment outcome studies among HIV-infected men who have sex with men who abuse crystal methamphetamine

2012

Men who have sex with men (MSM) have the highest incidence of HIV infection in the United States. One of the contributing factors to HIV spread among this group is...

Effects of physician-nurse substitution on clinical parameters: A systematic review and meta-analysis

2014

BACKGROUND: Physicians’ shortage in many countries and demands of high-quality and affordable care make physician-nurse substitution an appealing workforce strategy. The objective of this study is to conduct a systematic...

Hepatitis C in patients with human immunodeficiency virus infection: Diagnosis, natural history, meta-analysis of sexual and vertical transmission, and therapeutic issues

2000

Hepatitis C (HCV) infection occurs in as many as 33% of the patients with human immunodeficiency virus (HIV) infection. In view of their improved survival, liver disease will become more...

Treatment of severe or progressive Kaposi’s sarcoma in HIV-infected adults

2014

Background: Kaposi’s sarcoma remains the most common cancer in Sub-Saharan Africa and the second most common cancer in HIV-infected patients worldwide. Since the introduction of highly active antiretroviral therapy (HAART),...

Is there a role for primary care clinicians in providing shared care in HIV treatment? A systematic literature review

2012

BACKGROUND: Despite HIV being increasingly considered as a chronic illness, there is as yet no consensus about how primary care should be integrated with specialty care to provide optimal clinical...

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