Category Archives: Treatment
Diagnostic accuracy of the WHO clinical staging system for detection of immunologically defined advanced HIV disease: A systematic review and meta-analysis
Introduction People with advanced HIV disease (AHD) face high risks of severe illness and death. CD4 testing enables timely diagnosis and appropriate care, yet access remains limited in many settings....
Pharmacogenetics in tuberculosis-HIV coinfected populations: A systematic review of genetic variants influencing antiretroviral and anti-tuberculosis drug response
Pharmacogenetics is a concept designed to tailor medication based on genetic profile to improve efficacy and reduce adverse effects. This personalized strategy shows considerable potential for populations facing complicated therapeutic...
Pregnancy and neonatal outcomes of HIV infection in pregnant women in Iran: A systematic review and meta-analysis
Background HIV infection is a major public health concern among pregnant women globally. Beyond the risk of mother-to-child transmission, it can lead to serious complications and negative pregnancy and neonatal...
Body image and its associated factors among people living with HIV: A scoping review and implications for integrated care
People living with HIV (PLWH) face unique biopsychosocial challenges due to both infection and antiretroviral therapy (ART), one of which is body image disruption. This study comprehensively reviewed relevant studies...
A scoping review of mobile health for ART adherence in pregnant and breastfeeding women with HIV in sub-Saharan Africa: Preferences, acceptability, and privacy concerns
Background Interventions involving Mobile Health (mHealth) have shown promise to improve retention in care and adherence to antiretroviral therapy (ART) among pregnant or breastfeeding women living with HIV (PBWLH). However,...
Attrition rate of antiretroviral therapy and its influencing factors among Chinese people living with HIV/AIDS: A meta-analysis and system review
Objective To systematically evaluate the attrition rate of PWH undergoing ART and its influencing factors. Methods We systematically searched Embase, PubMed, Web of Science, The Cochrane Library, VIP, WanFang, CNKI,...
Barriers to and enablers of adherence to the treatment of active drug-sensitive tuberculosis in people living with HIV: A mixed method systematic review
BACKGROUND: Adherence to tuberculosis (TB) treatment is essential in improving treatment outcomes and reducing TB-related mortality. People living with HIV (PLWH) are at a higher risk of developing and dying...
Incidence of loss to follow-up among East African adults on antiretroviral therapy: A systematic review and meta-analysis
Background Individuals with human immunodeficiency virus receive antiretroviral treatment regardless of their clinical stage or CD4 count. While the “Universal Test and Treat” approach offers benefits, loss to follow-up remains...
HIV pre-exposure prophylaxis among people with criminal justice involvement in the United States: A systematic review
People with criminal justice involvement (PCJI) face a heightened risk of HIV yet remain underserved by prevention strategies such as pre-exposure prophylaxis (PrEP). This systematic review synthesizes current evidence on...
The reasons of late diagnosis in patients with HIV/AIDS: A meta-synthesis
PURPOSE: To comprehensively integrate qualitative findings on the reasons of late diagnosis in HIV/AIDS patients and to encourage timely clinic consultations for advisory purposes. METHODS: A qualitative systematic review utilizing...
Human milk oligosaccharides, microbiome, antiretroviral therapy and HIV infected mothers: Reasons to still promote breastfeeding in HIV context of lactating countries, a mini-narrative review
Breastfeeding is the preferred feeding for newborns during the first 6 months of life and until the age of 2 years or beyond. The benefits of breastfeeding remain significant, even in cases...
