Category Archives: Treatment

Exploring the potential of cognitive intra-individual variability in HIV care and research in adults with HIV: A concept analysis

2026

Cognitive intraindividual variability (IIV) refers to the variability in one’s ability to sustain consistent cognitive performance. This phenomenon is linked to the emergence of cognitive impairment and dementia. The aim...

Effectiveness of digital health interventions for improving antiretroviral therapy outcomes in people with HIV: Meta-analysis and trial sequential analysis of randomized controlled trials

2026

Background: Digital health interventions (DHIs) are increasingly used to support antiretroviral therapy (ART) management among people living with HIV. However, existing systematic reviews have largely focused on single intervention types or...

Factors associated with immunological non-response in HIV patients receiving antiretroviral therapy in Southeast Asia: A systematic review

2026

Objective This systematic review summarizes factors associated with immunological non-response (INR) among people with HIV on antiretroviral therapy (ART) in Southeast Asia. Methods We conducted a systematic search of PubMed,...

Exercise as a preventive and therapeutic strategy for non-communicable diseases in people living with HIV: Evidence, mechanisms and clinical implications

2026

Objective To synthesise evidence on exercise for preventing and managing non-communicable diseases (NCDs) among HIV clients, emphasising sub-Saharan Africa. Design Narrative review. Data sources Meta-analyses, randomised trials, cohort studies, mechanistic...

Integrated care models for HIV, diabetes and hypertension in sub-Saharan Africa: A systematic review of effectiveness, implementation and real-world applicability

2026

Background Sub-Saharan Africa faces a syndemic of HIV and non-communicable diseases (NCDs), particularly diabetes and hypertension. Integrated care models have been promoted to improve service efficiency and patient outcomes; however,...

Temporal shifts in antiretroviral therapy regimens and metabolic outcomes in people living with HIV: A systematic review and meta-analysis

2026

Introduction Antiretroviral therapy (ART) for people living with HIV has led to dramatically reduced mortality and improved life expectancy. This achievement is accompanied by a higher risk for metabolic and...

Condom use and associated factors among people living with HIV/AIDS on anti-retroviral therapy (ART) in Ethiopia: A systematic review and meta-analysis

2026

Condom use remains a crucial preventive measure for individuals undergoing antiretroviral therapy (ART) in the fight against HIV/AIDS. This review and meta-analysis aimed to determine the pooled prevalence of condom...

Oral health education interventions for people living with HIV: A scoping review of delivery approaches and reported outcomes

2026

Background People living with HIV (PLWH) experience a high burden of oral diseases that can impair daily function and affect adherence to HIV care. Oral health education has the potential...

Area-based measures of socioeconomic status in studies assessing health outcomes among people living with HIV in Canada and the USA: A scoping review

2026

OBJECTIVE: Area-based measures of socioeconomic status (SES) are increasingly used to study health disparities among people living with HIV (PLWH), with wide variation in how they are defined and applied...

Socio-cultural and systematic factors influencing fertility desire among women living with HIV: A systematic literature review

2026

Women and girls in Sub-Saharan Africa remain disproportionately affected by HIV. HIV care strategies can significantly reduce the risk of mother-to-child transmission of HIV. Women living with HIV (WLHIV) often...

Body image and its associated factors among people living with HIV: A scoping review and implications for integrated care

2026

People living with HIV (PLWH) face unique biopsychosocial challenges due to both infection and antiretroviral therapy (ART), one of which is body image disruption. This study comprehensively reviewed relevant studies...

Family-centred care for children and adolescents living with HIV in sub-Saharan Africa: A scoping review

2026

Introduction Children and adolescents living with HIV in sub-Saharan Africa (SSA) continue to face significant barriers to diagnosis, treatment adherence, retention in care and psychosocial support, despite progress in prevention...

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