Category Archives: Treatment

“What’s sex and gender got to do with it?” A scoping review of sex and gender-based analysis in pharmacoepidemiologic studies of medication adherence

2023

BACKGROUND: Medication taking is a complex multidimensional behaviour that may be impeded by a range of biological and psychosocial factors, including sex and gender. We aimed to synthesize how sex...

Disparities in healthcare access and utilization among people living with HIV in China: A scoping review and meta-analysis

2023

Background Healthcare disparities hinder the goal of ending the HIV pandemic by 2030. This review aimed to understand the status of healthcare disparities among people living with HIV (PLWH) in...

The innovative use of qualitative and mixed methods research to advance improvements along the HIV prevention and care continua

2022

PURPOSE OF REVIEW: Despite enormous advances in prevention and care modalities, HIV continues to burden populations around the globe and is largely driven by social and behavioral processes. Mixed methods...

Safety considerations in the management of hepatitis C and HIV co-infection

2023

INTRODUCTION: Both HCV and HIV are highly prevalent infections with current estimates of 57 and 38 million people infected worldwide, respectively. Oral antivirals can be curative for HCV and rescue...

The effect of antiretroviral therapy on the periodontal conditions of patients with HIV infection: A systematic review and meta-analysis

2023

Aim: To assess any differences (1) in the prevalence of periodontitis and necrotizing periodontal diseases, specifically necrotizing gingivitis (NG) and necrotizing periodontitis (NP) between HIV patients receiving antiretroviral therapy (HAART) and...

A scoping review of methods used to assess medication adherence in patients with chronic conditions

2022

BACKGROUND: Medication nonadherence of patients with chronic conditions is a complex phenomenon contributing to increased economic burden and decreased quality of life. Intervention development relies on accurately assessing adherence but...

Antiretroviral therapy management in adults with HIV during ICU admission

2022

The extended lifespan of people living with human immunodeficiency (HIV) and acquired immune deficiency syndrome (AIDS) (PLWHA) has increased the potential for ICU admissions unrelated to HIV infection. The objective...

Low-level viraemia: An emerging concern among people living with HIV in Uganda and across sub-Saharan Africa

2022

Attaining viral load (VL) suppression for over 95% of the people living with HIV on antiretroviral therapy is a fundamental step in enabling Uganda and other sub-Saharan African countries to...

Effect of social support interventions on adherence to antiretroviral therapy among people living with HIV: A systematic review and meta-analysis

2022

This systematic review and meta-analysis examined the effects of social support interventions (SSIs) on adherence to antiretroviral therapy (ART) among people living with HIV. We systematically searched Web of Science,...

First line antiretroviral treatment failure and its association with drug substitution and sex among children in Ethiopia: Systematic review and meta-analysis

2022

Antiretroviral Treatment (ART) has significantly decreased HIV-related morbidity and mortality among children despite the issue of drug resistance and subsequent treatment failure appearing as a challenge. Different studies have been...

Effectiveness and safety of statins on outcomes in patients with HIV infection: A systematic review and meta-analysis

2022

Statins are hypolipidaemic in human immunodeficiency virus (HIV) positive individuals. However, their effect on all-cause mortality and rate of discontinuation is unclear. We conducted a systematic review to evaluate the...

Transition interventions for adolescents on antiretroviral therapy on transfer from pediatric to adult healthcare: A systematic review

2022

Globally, adolescents living with HIV (ALHIV) experience poor health outcomes such as low retention in care, ART non-adherence and viral non-suppression. These outcomes coincide with the period during and after...

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