Category Archives: Treatment
Men who have sex with men is the high-risk drug resistance population: A meta-analysis of HIV-1 drug resistance profiles and trends in China
WHAT IS KNOWN AND OBJECTIVE: Except for the transmitted drug resistance (TDR)’s standard sampling and monitoring protocol, China’s HIV-1 pretreatment drug resistance (PDR) and acquired drug resistance (ADR) results vary...
Evaluating the impact of the COVID-19 pandemic on accessing HIV services in South Africa: A systematic review
Progress has been made towards controlling the Human Immunodeficiency Virus (HIV) epidemic in South Africa. However, the emergence of coronavirus disease 2019 (COVID-19) has disrupted access to health care. This...
Pre-treatment HIV-1 drug resistance in antiretroviral therapy-naive adults in Eastern Africa: A systematic review and meta-analysis
Background: Pre-treatment HIV drug resistance (PDR) may result in increased risk of virological failure and acquisition of new resistance mutations. With recently increasing ART coverage and periodic modifications of the guidelines...
How mHealth can contribute to improving the continuum of care: A scoping review approach to the case of human immunodeficiency virus in sub-Saharan Africa
Objectives: To determine mHealth’s contribution to improving the continuum of care in sub-Saharan Africa towards achieving treatment targets for human immunodeficiency virus (HIV) endorsed by the 2016 Political Declaration on...
A systematic review of digital interventions to improve ART adherence among youth living with HIV in sub-Saharan Africa
An estimated 3.4 million youth aged 15–24 years live with human immunodeficiency virus (HIV), a majority of whom reside in sub-Saharan Africa (SSA). Youth living with HIV (YLHIV) generally maintain...
Highly active antiretroviral therapy (HAART) and outcome of cervical lesions and high-risk HPV in women living with HIV (WLHIV): A systematic review and meta-analysis
BACKGROUND: Collating evidence on the impact of highly active antiretroviral therapy (HAART) on the outcome of cervical lesions or human papillomavirus (HPV) infection among women living with HIV (WLHIV) is...
Measuring patient engagement with HIV care in sub-Saharan Africa: a scoping study
INTRODUCTION: Engagement with HIV care is a multi-dimensional, dynamic process, critical to maintaining successful treatment outcomes. However, measures of engagement are not standardized nor comprehensive. This undermines our understanding of...
A clinical review of HIV integrase strand transfer inhibitors (INSTIs) for the prevention and treatment of HIV-1 infection
Integrase strand transfer inhibitors (INSTIs) have improved the treatment of human immunodeficiency virus (HIV). There are currently four approved for use in treatment-naA_ve individuals living with HIV; these include first...
The effect of antiretroviral therapy (HAART) on the periodontal conditions of patients with HIV-infection: A systematic review and meta-analysis
AIM: To assess any differences (1) in the prevalence of periodontitis and necrotizing periodontal diseases, specifically necrotizing gingivitis (NG) and necrotizing periodontitis (NP) between HIV patients receiving antiretroviral therapy (HAART)...
Same-day and rapid initiation of antiretroviral therapy in people living with HIV in Asia. How far have we come?
Human immunodeficiency virus (HIV) continues to be a major public health issue, and the effectiveness of HIV prevention, diagnosis, treatment, and care varies, particularly in the Asia-Pacific region. The rapid...
Oral health status of children and adolescents living with HIV undergoing antiretroviral therapy: A systematic review and meta-analysis
Antiretroviral therapy (ART) increases the survival of HIV-infected children, but might also bring in oral health-related side effects and increase their risks of oral diseases. The review compared the oral...
