Category Archives: Treatment

Analytical techniques for laboratory testing of HIV: A systematic review

2026

Acquired Immunodeficiency Syndrome (AIDS), caused by the Human Immunodeficiency Virus (HIV), remains a significant global public health threat. Effective antiretroviral therapy (ART) can reduce HIV viral loads to undetectable levels....

Closing diagnostic gaps in pediatric HIV: Innovations in point-of-care and digital monitoring with an Asia-Pacific implementation lens—A systematic review

2026

Background/Objectives: Pediatric HIV case-finding and monitoring remain constrained by delayed early infant diagnosis (EID), loss to follow-up, and limited viral load (VL) testing-challenges particularly consequential in the operationally diverse Asia-Pacific...

Person-centred HIV prevention services in sub-Saharan Africa: A scoping review

2026

BACKGROUND: In spite of numerous advancements in HIV prevention, there are still gaps that impede reaching key populations throughout sub-Saharan Africa. Traditional approaches usually overlook personal preferences, social context and...

Systematic scoping review on HIV services for males in Sub-Saharan Africa: Access, barriers, and research gaps

2026

BACKGROUND: Access to HIV services among men and boys in Sub-Saharan Africa is a significant public health challenge, exacerbated by cultural norms surrounding masculinity. This scoping review systematically investigates disparities...

Machine learning in HIV care and antiretroviral therapy: Systematic review

2026

BACKGROUND: Artificial intelligence (AI) is expanding across various medical fields, with machine learning (ML) being increasingly used to enhance patient management in diagnosis, prevention, and therapeutic care. OBJECTIVE: This study...

Gender-responsive and -transformative interventions in HIV, TB and malaria programmes: A review of evidence

2026

Gender-responsive and -transformative interventions are essential for tackling harmful social norms and discriminatory laws, policies, and practices that drive gender inequalities and health inequities especially for women, girls, and gender-diverse...

Risk factors for HIV-associated neurocognitive impairment and frailty in aging people with HIV in Latin America: A systematic review

2026

Background As people living with HIV (PWH) in Latin America and the Caribbean (LAC) have longer life expectancy due to improved access to antiretroviral therapy (ART), complications such as HIV-associated...

Perceptions about the relationship between HIV, antiretroviral therapy (ART), and fecundity in sub-Saharan Africa: Findings from a systematic scoping review

2026

Advances in antiretroviral therapy (ART) enable women living with HIV to safely conceive and give birth without vertical transmission. However, in sub-Saharan Africa, 1 in 6 people experience infertility and...

Interventions for thriving in HIV serodiscordant relationships in Sub-Saharan Africa: A scoping review

2026

Background HIV serodiscordant relationships, where one partner is HIV-positive and the other is HIV-negative, present unique challenges despite biomedical advances including U = U (Undetectable = Untransmittable). Effective interventions are crucial to support these...

Colliding wars: A systematic review on HIV responses in conflict-affected settings

2026

BACKGROUND: Armed conflicts are an escalating threat to public health, often marked by violence, poverty, displacement and weakened health systems-conditions that mirror the drivers of HIV transmission. AIM: This review...

Mental health of women with HIV: A qualitative meta-synthesis

2026

BACKGROUND: Women living with human immunodeficiency virus (HIV) experience significant psychological burdens due to biological and gendered factors such as pregnancy, childbirth and breastfeeding. However, a life course-based understanding of...

The prognosis characteristics of HIV/HBV co-infection after antiviral therapy: A comprehensive review

2026

Co-infection of HIV and HBV is still a major global public health concern. Co-infected people have a nearly threefold increased risk of end-stage liver disease, with a noticeably faster development...

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