Category Archives: Treatment

HIV infection and antiretroviral therapy impair liver function in people living with HIV: Systematic review and meta-analysis

2025

Background: The use of antiretroviral therapy (ART) has improved the lives of people living with HIV (PLWH). However, its use is associated with secondary complications, notably hepatotoxicity. This systematic review and...

Retention in HIV care among Southeast Asian people living with HIV: A systematic review and meta-analysis

2025

Background Despite the effectiveness of antiretroviral therapy (ART) in reducing HIV-related morbidity and mortality, the retention of HIV care remains suboptimal in Southeast Asia. Objective This systematic review and meta-analysis...

Estimating the effect of maternal viral load on perinatal and postnatal HIV transmission: A systematic review and meta-analysis

2025

Background Although a growing body of evidence supports zero risk of sexual HIV transmission from a person with sustained virological suppression, known as U=U (undetectable equals untransmittable), data have been...

Social and structural determinants of health influencing HIV risk and participation across the HIV care cascade

2025

Key take-home messages

Transitioning to adult HIV care: Challenges and evidence-based practices

2025

Key take-home messages

Aging and HIV: Recent findings in contributing factors

2025

Background: Aging among people living with HIV (PLWH) presents multifaceted challenges influenced by antiretroviral therapy (ART), chronic inflammation, viral coinfections, stigma, multimorbidity, and immunosuppression. Methods: This review synthesizes recent research...

Evaluating HIV drug resistance in the Middle East and North Africa and its associated factors: A systematic review

2025

OBJECTIVE: One of the obstacles to achieving successful treatment of HIV infections is the development and spread of mutations linked to resistance. Thus, it is important to monitor the prevalence...

Family influences on antiretroviral therapy adherence in youth with HIV in the United States: A systematic review

2025

HIV poses a significant issue in the United States and understanding how HIV-positive populations adhere to treatments, specifically with antiretroviral therapy (ART), is vital for researchers to find approaches to...

Depression and associated factors among human immunodeficiency virus-positive pregnant women in sub-Saharan Africa: Systematic review and meta-analysis

2025

BACKGROUND: Despite its severe impact on both maternal and fetal health, antenatal depression has not received as much attention in the healthcare community as postnatal depression. Comprehensive evidence is very...

Improving communication: A narrative synthesis of interventions for HIV disclosure to pediatric populations

2025

PURPOSE OF REVIEW: HIV remains a significant global public health concern, affecting millions worldwide, including children. Disclosure of HIV status to infected children holds several benefits, yet rates of disclosure...

The impact of homelessness and housing insecurity on HIV

2025

Homelessness is a global problem with wide-ranging causes and contexts. People experiencing homelessness and unstable housing (HUH) are disproportionately affected by HIV and face worse treatment outcomes than those with...

Health service utilization of Black immigrant women residing in the United States: A systematic review

2024

Black immigrants constitute a rapidly growing population group in the U.S. A comprehensive understanding of health services used by Black immigrant women is necessary to support the complex needs of...

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