Category Archives: Treatment
Barriers to uptake of long-acting antiretroviral products for treatment and prevention of human immunodeficiency virus (HIV) in high-income countries
Long-acting injectable antiretroviral therapy (LAI-ART) for the treatment and prevention of human immunodeficiency virus (HIV) holds great potential to shift treatment paradigms by offering an alternative to daily oral medication....
Review of antiretroviral therapy coverage in 10 highest burden HIV countries in Africa: 2015–2020
Africa is responsible for two-thirds of the global total of new HIV infections. South Africa, Nigeria, Mozambique, Uganda, Tanzania, Zambia, Zimbabwe, Kenya, Malawi, and Ethiopia were responsible for 80% of...
The effects of intimate partner violence on women’s risk of HIV acquisition and engagement in the HIV treatment and care cascade: A pooled analysis of nationally representative surveys in sub-Saharan Africa
Background Achieving the 95-95-95 targets for HIV diagnosis, treatment, and viral load suppression to end the HIV epidemic hinges on eliminating structural inequalities, including intimate partner violence (IPV). Sub-Saharan Africa...
Isoniazid preventive therapy for prevention of tuberculosis among people living with HIV in ethiopia: A systematic review of implementation and impacts
BACKGROUND: Tuberculosis (TB) is a major cause of morbidity and mortality in people living with HIV (PLWHIV). Isoniazid preventive therapy (IPT) prevents TB in PLWHIV, but estimates of its effects...
The impacts of COVID-19 pandemic on service delivery and treatment outcomes in people living with HIV: A systematic review
INTRODUCTION: The COVID-19 epidemic and various control and mitigation measures to combat the widespread outbreak of the disease may affect other parts of health care systems. There is a concern...
A review of factors associated with methadone maintenance treatment adherence and retention in Vietnam
BACKGROUND: Starting in 2008, Vietnam’s national MMT program expanded quickly, but it is struggling with increasing attrition rates and poor adherence among patients. Several studies have reported on MMT retention...
Web-based service provision of HIV, viral hepatitis, and sexually transmitted infection prevention, testing, linkage, and treatment for key populations: Systematic review and meta-analysis
BACKGROUND: Despite the growth of web-based interventions for HIV, viral hepatitis (VH), and sexually transmitted infections (STIs) for key populations, the evidence for the effectiveness of these interventions has not...
Perinatal outcomes associated with combination antiretroviral therapy compared with monotherapy
Objectives: Increasing numbers of women living with HIV (WLHIV) worldwide receive combination antiretroviral therapy (cART) during pregnancy. We aimed to assess the risk of adverse perinatal outcomes in pregnant WLHIV receiving...
Mental health problems across the HIV care continuum for adolescents living with HIV in sub-Saharan Africa: A scoping review
Mental health problems (e.g., anxiety, depression) are frequently experienced by adolescents living with HIV (ALWH) and can worsen HIV-related outcomes. This scoping review synthesizes the existing research on ALWHs’ mental...
Virological failure and adherence to antiretroviral therapy in adolescents and young adults living with human immunodeficiency virus
Objective: HIV (human immunodeficiency virus) infection remains a major public health challenge. Infected young people at any age are less likely to adhere to care in a timely manner and to...
