Category Archives: Treatment
Transition interventions for adolescents on antiretroviral therapy on transfer from pediatric to adult healthcare: A systematic review
Globally, adolescents living with HIV (ALHIV) experience poor health outcomes such as low retention in care, ART non-adherence and viral non-suppression. These outcomes coincide with the period during and after...
Body image in children and adolescents diagnosed with the human immunodeficiency virus: A systematic review
CONTEXT: The relationship with body image, which is the way the body presents itself to each subject, can be aggravated in children and adolescents diagnosed with an human immunodeficiency virus...
The effects of intimate partner violence on women’s risk of HIV acquisition and engagement in the HIV treatment and care cascade: A pooled analysis of nationally representative surveys in sub-Saharan Africa
Background Achieving the 95-95-95 targets for HIV diagnosis, treatment, and viral load suppression to end the HIV epidemic hinges on eliminating structural inequalities, including intimate partner violence (IPV). Sub-Saharan Africa...
Isoniazid preventive therapy for prevention of tuberculosis among people living with HIV in ethiopia: A systematic review of implementation and impacts
BACKGROUND: Tuberculosis (TB) is a major cause of morbidity and mortality in people living with HIV (PLWHIV). Isoniazid preventive therapy (IPT) prevents TB in PLWHIV, but estimates of its effects...
The impacts of COVID-19 pandemic on service delivery and treatment outcomes in people living with HIV: A systematic review
INTRODUCTION: The COVID-19 epidemic and various control and mitigation measures to combat the widespread outbreak of the disease may affect other parts of health care systems. There is a concern...
A review of factors associated with methadone maintenance treatment adherence and retention in Vietnam
BACKGROUND: Starting in 2008, Vietnam’s national MMT program expanded quickly, but it is struggling with increasing attrition rates and poor adherence among patients. Several studies have reported on MMT retention...
Web-based service provision of HIV, viral hepatitis, and sexually transmitted infection prevention, testing, linkage, and treatment for key populations: Systematic review and meta-analysis
BACKGROUND: Despite the growth of web-based interventions for HIV, viral hepatitis (VH), and sexually transmitted infections (STIs) for key populations, the evidence for the effectiveness of these interventions has not...
The prevalence of HIV-infected patients with virological suppression but a CD4+ T-cell count of ≤ 200 cells/mm3 after highly active antiretroviral therapy initiation: A meta-analysis
Highly active antiretroviral therapy (HAART) strongly inhibits HIV replication. However, many patients show suboptimal immune recovery (SIR), as defined by virological suppression (i.e. low viral load) with a CD4+ T-cell count...
Factors associated with post-treatment control of viral load in HIV-infected patients: A systematic review and meta-analysis
BACKGROUND: This study aimed to investigate the factors associated with maintenance of viral suppression after antiretroviral therapy (ART) discontinuation. METHODS: Databases were searched for studies published between 1 January, 2011,...
Perinatal outcomes associated with combination antiretroviral therapy compared with monotherapy
Objectives: Increasing numbers of women living with HIV (WLHIV) worldwide receive combination antiretroviral therapy (cART) during pregnancy. We aimed to assess the risk of adverse perinatal outcomes in pregnant WLHIV receiving...
Mental health problems across the HIV care continuum for adolescents living with HIV in sub-Saharan Africa: A scoping review
Mental health problems (e.g., anxiety, depression) are frequently experienced by adolescents living with HIV (ALWH) and can worsen HIV-related outcomes. This scoping review synthesizes the existing research on ALWHs’ mental...
