Category Archives: Treatment

A comparative review of mobile health and electronic health utilization in sub-Saharan African countries

2019

This study distinguished between the application of e-health and m-health technologies in sub-Saharan African (SSA) countries based on the dimensions of use, targeted diseases or health conditions, locations of use,...

Health literacy and health outcomes in persons living with HIV disease: A systematic review

2019

Low health literacy is associated with challenges for those living with HIV including medication non-adherence and poorer health outcomes. The aim of this study was to systematically review the literature...

HIV-related care for transgender people: A systematic review of studies from around the world

2019

RATIONALE: Transgender people face unique challenges, such as structural, interpersonal, and individual vulnerabilities to chronic diseases. Stigma and prejudice may hamper their access to health care and prevent their inclusion...

Is co-location of services with HIV care associated with improved HIV care outcomes? A systematic review

2019

This systematic review identifies models of service co-location, a structural intervention strategy to remove barriers to HIV care and services, and examines their associations with HIV care outcomes. A cumulative...

A systematic mixed studies review of the intersections of social-ecological factors and HIV stigma in people living with HIV in the U.S. south

2019

The role of stigma on psychological wellness and treatment outcomes in people living with HIV (PLWH) has been well documented. However, within the context of the southern United States, the...

Managing pharmacotherapy in people living with HIV and concomitant malignancy

2019

OBJECTIVE: To describe data with selected malignancies in people living with HIV (PLWH) and HIV in individuals affected by both conditions and to summarize drug-drug interactions (DDIs) with clinical recommendations...

Optimizing pediatric dosing recommendations and treatment management of antiretroviral drugs utilizing therapeutic drug monitoring data in children living with HIV

2019

INTRODUCTION: This review summarises the current dosing recommendations for antiretroviral drugs (ARVs) in the international pediatric guidelines of the World Health Organisation (WHO), US Department of Health and Human Services...

Dolutegravir-rilpivirine, dual antiretroviral therapy for the treatment of HIV-1 infection

2019

OBJECTIVE: To review the efficacy and safety of dolutegravir (DTG) with rilpivirine (RPV) as a dual therapy regimen in the treatment of HIV-1 infection. DATA SOURCES: A literature search was...

Adverse effects of chronic treatment with the main subclasses of highly active antiretroviral therapy: A systematic review

2019

OBJECTIVES: The aim of the review was to elucidate the adverse effects of chronic treatment with the main subclasses of highly active antiretroviral therapy (HAART). METHODS: A systematic review was...

Pharmacokinetics and safety of the integrase inhibitors elvitegravir and dolutegravir in pregnant women with HIV

2019

OBJECTIVE: To synthesize data on the pharmacokinetics and safety of dolutegravir and elvitegravir in pregnant women living with HIV. DATA SOURCES: A PubMed, EMBASE, Web of Science, and Google Scholar...

In utero exposure to HIV and/or antiretroviral therapy: A systematic review of preclinical and clinical evidence of cognitive outcomes

2019

INTRODUCION: With the increasing number of children exposed to HIV or antiretroviral therapy in utero, there are concerns that this population may have worse neurodevelopmental outcomes compared to those who...

A systematic review and cost-effectiveness analyses of the new World Health Organization guidelines for the treatment of HIV-positive adults in India

2019

Background: The World Health Organization (WHO) in 2013 has revised its guidelines on antiretroviral therapy (ART) treatment for human immunodeficiency virus (HIV)-positive adults and further updated it in 2016. Based...

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