Category Archives: Treatment
Possible prevention of neurodevelopmental consequences of vertical HIV transmission in early childhood? A systematic review
BACKGROUND: Children infected with the Human Immunodeficiency Virus (HIV) exhibit the lowest neurodevelopmental scores. Mother-to-child-transmission prevention include perinatally and early antiretroviral therapy (ART) although long-term effects of in utero exposure...
Syndemic interactions between HIV/AIDS, mental health conditions, and non-communicable diseases in sub-Saharan Africa: A scoping review of contributing factors
INTRODUCTION: The syndemic framework provides a critical lens for understanding the complex interplay between HIV/AIDS, mental health (MH) conditions, and non-communicable diseases (NCDs) in Africa. This scoping review explores how...
Acceptability, needs, concerns, and barriers to digital-based interventions for the prevention of mother-to-child transmission of HIV: Systematic review and qualitative meta-aggregation
BACKGROUND: Digital-based interventions have the potential to support initiatives for the prevention of mother-to-child HIV transmission (PMTCT). Nevertheless, reviews to explore experiences and perspectives toward digital-based interventions in mothers living...
Social determinants of adherence to antiretroviral therapy among adolescents and young people living with HIV: A scoping review
OBJECTIVE: To map scientific evidence related to social determinants of adherence to antiretroviral therapy among adolescents and young people living with HIV. METHOD: Scoping review according to JBI methodology, carried...
Studied factors and metrics of patient portal use among people with HIV: A rapid scoping review
For people living with HIV (PLHIV), patient portals could facilitate access to personal health records while promoting self-management and retention in care. Given the apparent heterogeneity in the studied factors...
Incidence and predictors of attrition among children on antiretroviral therapy in Ethiopia: A systematic review and meta-analysis
Objective To estimate the pooled attrition rate among HIV-infected children receiving antiretroviral therapy (ART) and identify predictors of attrition in Ethiopia. Design Systematic review and meta-analysis. Data sources PubMed, HINARI,...
Oral pre-exposure prophylaxis initiation, continuation and adherence among pregnant and postpartum women receiving antenatal and postnatal care: A systematic review
INTRODUCTION: In 2023, one-fourth of new HIV acquisitions in children globally resulted from vertical transmission following incident HIV during pregnancy or breastfeeding. Oral pre-exposure prophylaxis (PrEP) with tenofovir disoproxil and...
The magnitude and patterns of acquired drug resistanace mutations and circulating HIV-1 subtypes in HIV patients in Tanzania, a systematic review and meta-analysis
The emergence and spread of HIV drug resistance mutations (DRMs) pose a threat to current and future treatment options. To inform policy, this review aimed to determine the magnitude and...
Prevalence of low-level viremia and related influencing factors among people living with HIV in China: A systematic review and meta-analysis
Introduction The promotion and application of ART have significantly reduced the mortality rate of AIDS patients in China, but the problem of LLV that follows cannot be ignored. LLV is...
Effects of Moringa oleifera supplementation on immune and nutritional biomarkers in adults living with HIV: A systematic review and meta-analysis
BACKGROUND: Moringa oleifera (MO) is widely used as an adjunctive therapy for individuals living with HIV (PLWH) due to its nutritional and immune-modulating properties. OBJECTIVE: To systematically evaluate the effects...
Effectiveness of conditional cash transfers for uptake and retention in HIV prevention of mother-to-child transmission services in low- and middle-income countries: A systematic review and meta-analysis
OBJECTIVE: The objective of this systematic review was to synthesize the best available evidence on the effectiveness of conditional cash transfers for the uptake and retention in prevention of mother-to-child...
Determinants of HIV related mortality in African children on antiretroviral therapy: Clinical and immunological insights from a systematic review and meta-analysis
BACKGROUND: The HIV epidemic in Africa is still a serious public health concern, particularly for children who are more vulnerable to its negative consequences. Various studies carried out in different...
