Category Archives: Treatment
Effectiveness of ombitasvir/paritaprevir/ritonavir, dasabuvir for HCV in HIV/HCV coinfected subjects: A comprehensive analysis
BACKGROUND: Data on the treatment of patients with hepatitis C virus (HCV)/human immunodeficiency virus (HIV) coinfection remains limited. A comprehensive analysis was performed to evaluate the efficacy and safety of...
Content guidance for mobile phones short message service (SMS)-based antiretroviral therapy adherence and appointment reminders: A review of the literature
Mobile phones are increasingly being used to support health activities, including the care and management of people living with HIV/AIDS. Short message service (SMS) has been explored as a means...
Epidemiology of depressive disorders in people living with HIV in Africa: A systematic review and meta-analysis: Burden of depression in HIV in Africa
OBJECTIVE: The burden of HIV infection is higher in Africa where 70% of people living with HIV (PLHIV) resides. Since depression can negatively impact the course of HIV infection, it...
Unintended pregnancy in women living with HIV in sub-Saharan Africa: A systematic review and meta-analysis
In 2014, about 1.5 million pregnancies occurred among HIV-positive women in low and middle-income countries. To pool magnitude and factors associated with unintended pregnancy in women living with HIV in...
Physical activity and HIV in sub-Saharan Africa: A systematic review of correlates and levels
Background: Self-management strategies such as physical activity (PA) can address disability and optimize mental, physical, social and economic outcomes for persons living with HIV (PLWH). Understanding factors that influence PA...
Risk of sexual transmission of human immunodeficiency virus with antiretroviral therapy, suppressed viral load and condom use: A systematic review
BACKGROUND: The Public Health Agency of Canada reviewed sexual transmission of HIV between serodiscordant partners to support examination of the criminal justice system response to HIV nondisclosure by the Department...
Integration of neonatal and child health interventions with pediatric HIV interventions in global health
Background/Objectives: In the last decade, many strategies have called for integration of HIV and child survival platforms to reduce missed opportunities and improve child health outcomes. Countries with generalized HIV...
Antiretroviral resistance testing in HIV-positive people
BACKGROUND: Resistance to antiretroviral therapy (ART) among people living with human immunodeficiency virus (HIV) compromises treatment effectiveness, often leading to virological failure and mortality. Antiretroviral drug resistance tests may be...
Being HIV positive and staying on antiretroviral therapy in Africa: A qualitative systematic review and theoretical model
BACKGROUND: Adherence to antiretroviral therapy (ART) and long-term uninterrupted engagement in HIV care is difficult for HIV-positive people, and randomized trials of specific techniques to promote adherence often show small...
HIV, sexually transmitted infection, and substance use continuum of care interventions among criminal justice-involved black men who have sex with men: A systematic review
BACKGROUND: Because Black men who have sex with men (BMSM) experience high rates of both HIV and incarceration relative to other groups, the various stages of criminal justice involvement may...
Knowledge of HIV and related best practices among non-HIV specific health care providers
Key take-home messages One Canadian and several U.S. surveys have consistently shown a lack of HIV-related knowledge, awareness of HIV-related guidelines, and failure to screen for HIV among non-HIV specific...