Category Archives: Treatment
Overview of systematic reviews on strategies to improve treatment initiation, adherence to antiretroviral therapy and retention in care for people living with HIV: Part 1
OBJECTIVES: We sought to map the evidence and identify interventions that increase initiation of antiretroviral therapy, adherence to antiretroviral therapy and retention in care for people living with HIV at...
Cancer in youth living with HIV (YLWHIV): A narrative review of the access to oncological services among YLWHIV and the role of economic strengthening in child health
Youth Living with HIV/AIDS (YLWHIV) have a higher risk of developing immunodeficiency related illnesses including certain cancers than their general population counterparts of the same age. This narrative review of...
ART uptake and adherence among women who use drugs globally: A scoping review
OBJECTIVE: To assess the state of peer-reviewed literature surrounding uptake and adherence of antiretroviral therapy (ART) among HIV-positive women who use drugs (WWUD). METHODS: Consistent with PRISMA-ScR guidelines, we conducted...
Interventions to improve HIV care continuum outcomes among individuals released from prison or jail: Systematic literature review
BACKGROUND: HIV care continuum outcomes deteriorate among people returning from incarceration. Interventions to improve care outcomes post-incarceration have been characterized by substantial heterogeneity in approach, outcome metrics, and results. A...
Antiretroviral therapy-associated metabolic complications: Review of the recent studies
The extensive utilization of antiretroviral therapy (ART) has successfully improved human immunodeficiency virus (HIV)-associated complications. The incidence of opportunistic infections is decreased by the viral load suppression and the CD4...
Implications of COVID-19 in high burden countries for HIV/TB: A systematic review of evidence
BACKGROUND: The triple burden of COVID-19, tuberculosis and human immunodeficiency virus is one of the major global health challenges of the twenty-first century. In high burden HIV/TB countries, the spread...
Risk of failure in dual therapy versus triple therapy in naive HIV-patients: A systematic review and meta-analysis
BACKGROUND: Several attempts have been made to test different drug-sparing strategies to reduce the drug-burden and drug-related toxicities. OBJECTIVE: The objective of this meta-analysis was to evaluate the relative risk...
Utility of short message service (SMS) for remote data collection for HIV in low- and middle-income countries
PURPOSE OF REVIEW: Short message system (SMS) communication is widespread in low- and middle-income countries (LMICs), and may be a viable approach to address challenges with in-person data collection for...
Exercise and antiretroviral adherence in adults living with HIV: A systematic review
This systematic review assessed the relationship between exercise and ART adherence in adults living with HIV. A comprehensive search through June 2020 for relevant studies was conducted, and PRISMA guidelines...
The effect of successful antiretroviral therapy on immune activation and Reconstitution in HIV infected adults: A systematic review and meta-analysis
We performed a systematic review and meta-analysis to investigate the impact of antiretroviral therapy (ART) on immune activation and reconstitution in people living with human immunodeficiency virus (PLWH). The PubMed...
Methadone maintenance therapy service components linked to improvements in HIV care cascade outcomes: A systematic review of trials and observational studies
BACKGROUND: The beneficial links between engagement in methadone maintenance therapy (MMT) and HIV treatment outcomes have been extensively described. Nevertheless, people who use drugs (PWUD) continue to experience suboptimal HIV...
