Category Archives: Treatment
impact of pre-antiretroviral therapy CD4 counts on drug resistance and treatment failure: A systematic review
The continuous rising of HIV drug resistance in low- and middle-income countries and its impact on treatment failure is a growing threat for the HIV treatment response. This review aimed...
Impact of mobile phone-based interventions on methamphetamine use and high-risk sexual behaviors in men who have sex with men (MSM): A systematic review
Background: Today, increased use of methamphetamine in homosexual men is associated with high-risk sexual behaviors and (HIV) epidemic. Mobile phone-based interventions are an accessible and rapid method to provide healthcare...
mHealth and opportunities in anti-retroviral adherence in HIV, a diverse group of patients with diverse and unique opportunities: A narrative review
BACKGROUND: Antiretrovirals (ARVs) are key in the management of human immunodeficiency virus (HIV). While no cure exists, ARVs help patients live healthy lives and prevent transmission to others. However, adherence...
Social and structural determinants of household support for art adherence in low- and middle-income countries: A systematic review
Adherence to HIV antiretroviral therapy (ART) is a crucial factor in health outcomes for people living with HIV (PLWH). Interventions to support ART adherence are increasingly focused on the household...
A systematic review and meta-analyses on initiation, adherence and outcomes of antiretroviral therapy in incarcerated people
BACKGROUND: Incarcerated people are at increased risk of human immunodeficiency virus (HIV) infection relative to the general population. Despite a high burden of infection, HIV care use among prison populations...
Risk factors for loss to follow-up from antiretroviral therapy programmes in low- and middle-income countries: A systematic review and meta-analysis
INTRODUCTION: Loss to follow up (LTFU) rates from antiretroviral treatment (ART) programmes in low- and middle-income countries (LMIC) are high, forming an important risk factor for poor treatment outcomes and...
Pre-exposure prophylaxis (PrEP) for HIV prevention among men who have sex with men (MSM): A scoping review on PrEP service delivery and programming
Pre-exposure prophylaxis (PrEP) is an evidence-based new biomedical HIV prevention intervention, which involves the pre-emptive use of daily (or event-based) antiretroviral drugs, to reduce risk of HIV acquisition if exposed....
Pharmacokinetics, placental and breast milk transfer of antiretroviral drugs in pregnant and lactating women living with HIV
BACKGROUND: Remarkable progress has been achieved in the identification of HIV infection in pregnant women and in the prevention of vertical HIV transmission through maternal antiretroviral treatment (ART) and neonatal...
Efficacy and safety of direct acting antiviral regimens for hepatitis C virus and human immunodeficiency virus co-infection: Systematic review and network meta-analysis
BACKGROUND AND AIM: Various all-oral direct-acting antiviral (DAA) regimens are being widely used in the treatment of human immunodeficiency virus (HIV)/hepatitis C virus (HCV) co-infected patients; however, the comparative efficacy...
