Category Archives: Treatment

A review of usability evaluation methods and their use for testing eHealth HIV interventions

2020

PURPOSE OF REVIEW: To provide a comprehensive review of usability testing of eHealth interventions for HIV. RECENT FINDINGS: We identified 28 articles that assessed the usability of eHealth interventions for...

Factors Related to Hair Antiretroviral Concentration: A Systematic Review of Global Literature

2019

Assessment of antiretroviral (ARV) concentration in hair (hair antiretroviral concentration [HAC]) is one of the latest non-invasive innovations for measuring long-term ARV adherence. We performed a systematic review following Preferred...

Aging with HIV

2019

PURPOSE OF REVIEW: This review points out unmet medical needs and open research questions of older adults living with HIV. Starting from the definition of aging in HIV, it explores...

The pharmacogenetics of efavirenz metabolism in children: The potential genetic and medical contributions to child development in the context of long-term ARV treatment

2020

Efavirenz (EFV) is a well-known, effective anti-retroviral drug long used in first-line treatment for children and adults with HIV and HIV/AIDS. Due to its narrow window of effective concentrations, between...

Interventions to improve medication adherence in adolescents with HIV: A systematic review and meta-analysis

2020

As of 2017, 1.8 million people living with HIV (PLWH) were adolescents between ages 10 and 19, accounting for 5% of all PLWH and 590,000 people between the ages 15...

Adolescent mothers affected by HIV and their children: A scoping review of evidence and experiences from sub-Saharan Africa

2020

While adolescents have received increasing attention in the global HIV response and international strategies and commitments, adolescent mothers and their children remain largely overlooked in research, funding and, programming for...

Sexual and reproductive health of women living with HIV in Muslim-majority countries: A systematic mixed studies review

2020

BACKGROUND: The number of women living with the human immunodeficiency virus (WLHIV) in Muslim-majority countries has increased significantly in the last decade. These women are often marginalized and face insecure...

Antiretroviral therapy and detection of high-grade cervical intraepithelial neoplasia (CIN2+) at post-CIN management follow-up among women living with HIV: A systematic review and meta-analysis

2020

BACKGROUND: We evaluated the association of antiretroviral therapy (ART), CD4+ count and HIV plasma viral load (PVL) on high-grade cervical intraepithelial neoplasia (CIN2+) detection at follow-up after CIN management among...

The role of the clinical pharmacist in the management of people living with HIV in the modern antiretroviral era

2019

As the HIV epidemic has evolved, so too has the role of the clinical pharmacist (CP) in the management of people living with HIV (PLWH). The modern antiretroviral therapy (ART)...

Interventions to improve antiretroviral therapy adherence among adolescents and youth in low- and middle-income countries: A systematic review 2015-2019

2020

Adolescents and youth living with HIV have poorer antiretroviral treatment (ART) adherence and viral suppression outcomes than all other age groups. Effective interventions promoting adherence are urgently needed. We reviewed...

Treating progressive disseminated histoplasmosis in people living with HIV

2020

BACKGROUND: Progressive disseminated histoplasmosis (PDH) is a serious fungal infection that affects people living with HIV. The best way to treat the condition is unclear. OBJECTIVES: We assessed evidence in...

Childhood tuberculosis treatment outcome and its association with HIV co-infection in Ethiopia: A systematic review and meta-analysis

2020

Background: Tuberculosis is the second leading cause of death from an infectious disease worldwide, next to HIV. Hence, initiating and determining the national tuberculosis treatment program and outcome is crucial....

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