Category Archives: Treatment

The effectiveness of treatment supporter interventions in antiretroviral treatment adherence in sub-Saharan Africa: A systematic review and meta-analysis

2020

This systematic review and meta-analysis evaluated the effectiveness of treatment supporter interventions (TSI) in improving ART adherence and viral suppression among adults living with HIV (PLWH) in sub-Saharan Africa. This...

Two’s a company, three’s a crowd: A review of initiating or switching to a two-drug antiretroviral regimen in treatment-naive and treatment-experienced patients living with HIV-1

2020

INTRODUCTION: As HIV has become a manageable chronic condition, a renewed and increased interest in challenging traditional three-drug HIV therapies and moving toward two-drug regimens (2DR) for initial or maintenance...

Predictors of adherence to antiretroviral therapy among PLHIV

2019

Adherence to antiretroviral therapy (ART) is of paramount importance to achieve the optimum control of viral load and progression of disease among people living with HIV (PLHIV). An overview of...

Sexual and reproductive health of women living with HIV in Muslim-majority countries: A systematic mixed studies review

2020

BACKGROUND: The number of women living with the human immunodeficiency virus (WLHIV) in Muslim-majority countries has increased significantly in the last decade. These women are often marginalized and face insecure...

HIV/AIDS treatment failure and associated factors in Ethiopia: Meta-analysis

2020

BACKGROUND: The national burden of human immunodeficiency virus treatment failure and associated factors in the Ethiopian context is required to provide evidence towards a renewed ambitious future goal. METHODS: We...

Attrition of HIV-positive children from HIV services in low and middle-income countries

2019

INTRODUCTION: Identification and retention of HIV-positive children in HIV services is essential to ensure optimal health outcomes. This systematic review and meta-analysis examines the magnitude of attrition [loss to follow-up...

Impact of lay health worker programmes on the health outcomes of mother-child pairs of HIV exposed children in Africa: A scoping review

2019

BACKGROUND: Increased demand for healthcare services in countries experiencing high HIV disease burden and often coupled with a shortage of health workers, has necessitated task shifting from professional health workers...

Loss to follow-up from antiretroviral therapy clinics: A systematic review and meta-analysis of published studies in South Africa from 2011 to 2015

2019

Background: South Africa has the largest antiretroviral therapy (ART) programme in the world. To optimise programme outcomes, it is critical that patients are retained in care and that retention is...

Analysis of systematic reviews of medication adherence interventions for persons with HIV, 1996–2017

2019

This overview of reviews summarizes the evidence from systematic reviews (SR) on the effectiveness of antiretroviral therapy (ART) adherence interventions for people with HIV (PWH) and descriptively compares adherence interventions...

Using discrete choice experiments to develop and deliver patient-centered psychological interventions: A systematic review

2020

Developing and/or tailoring psychological interventions to align with patient preferences is a critical component of patient-centered care and has the potential to improve patient engagement and treatment outcomes. Discrete choice...

HBV infection in HIV-driven immune suppression

2019

Worldwide, approximately 10% of all human immunodeficiency virus (HIV)-infected people are also chronically coinfected with hepatitis B virus (HBV). HBV infection has a poor prognosis in HIV-positive people and has...

Adherence to antiretroviral therapy among HIV patients in India: A systematic review and meta-analysis

2020

We conducted a systematic review and meta-analysis to estimate the prevalence of adherence to antiretroviral therapy (ART) in India, the third largest HIV epidemic in the world. We identified peer...

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