Category Archives: Treatment

Using discrete choice experiments to develop and deliver patient-centered psychological interventions: A systematic review

2020

Developing and/or tailoring psychological interventions to align with patient preferences is a critical component of patient-centered care and has the potential to improve patient engagement and treatment outcomes. Discrete choice...

HBV infection in HIV-driven immune suppression

2019

Worldwide, approximately 10% of all human immunodeficiency virus (HIV)-infected people are also chronically coinfected with hepatitis B virus (HBV). HBV infection has a poor prognosis in HIV-positive people and has...

Adherence to antiretroviral therapy among HIV patients in India: A systematic review and meta-analysis

2020

We conducted a systematic review and meta-analysis to estimate the prevalence of adherence to antiretroviral therapy (ART) in India, the third largest HIV epidemic in the world. We identified peer...

Efficacy and safety of raltegravir-based dual therapy in AIDS patients: A meta-analysis of randomized controlled trials

2019

Background: The life expectancy for HIV-infected individuals has improved dramatically because of improvements in antiretroviral therapy (ART). Today, a simplified two-drug regimen enhances adherence and treatment satisfaction by reducing adverse...

HIV viral resuppression following an elevated viral load: A systematic review and meta-analysis

2019

INTRODUCTION: Guidelines for antiretroviral therapy recommend enhanced adherence counselling be provided to individuals with an initial elevated viral load before making a decision whether to switch antiretroviral regimen. We undertook...

Trend of HIV-1 drug resistance in China: A systematic review and meta-analysis of data accumulated over 17 years (2001-2017)

2020

Background: The emergence and spread of HIV-1 drug resistance may compromise HIV control globally. In response to HIV/AIDS epidemic, China launched national HIV/AIDS treatment program in 2003, and started to...

Treatment failure and associated factors among first line patients on highly active antiretroviral therapy in Ethiopia: A systematic review and meta-analysis

2019

Background: Antiretroviral therapy (ART) restores immune function and reduces human immunodeficiency virus (HIV) related adverse outcomes. The results of previous studies in Ethiopia were replete with inconsistent findings; nonexistence of...

Immunological and virological responses in older HIV-infected adults receiving antiretroviral therapy: An evidence-based meta-analysis

2020

Millions of people living with the human immunodeficiency virus (HIV) have received antiretroviral therapy (ART). Older adults make up a significant portion of these individuals, however, the immunological and virological...

Social and structural determinants of HIV treatment and care among Hispanic women and Latinas living with HIV infection in the United States: A qualitative review: 2008-2018

2019

Purpose: In 2017, among all women in the United States, Hispanic women and Latinas (Hispanics/Latinas) accounted for 16% of women with HIV. Populations with high HIV disparities, including Hispanics/Latinas, experience...

Child-centred care in HIV service provision for children in resource constrained settings: A narrative review of literature

2019

Introduction: Child-centred care approaches are increasingly gaining traction in healthcare; and are being applied in the delivery of HIV care for children in resource constrained settings. However, very little is...

HIV prevention cascade theory and its relation to social dimensions of health: A case for Nigeria

2019

Background: Nigeria has the second largest HIV epidemic in the world and one of the highest rates of new infection in sub-Saharan Africa. Within the last three decades, majority of...

A client-centered relational framework on barriers to the integration of HIV and substance use services: A systematic review

2019

BACKGROUND: Given the close connection between human immunodeficiency virus (HIV) infection and substance use disorder (SUD), access to integrated HIV and SUD services is critical for individuals experiencing both challenges...

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