Category Archives: Treatment
Psychosocial and behavioural interventions towards HIV risk reduction for serodiscordant couples in Africa: A systematic review
Background: Sexual transmission of HIV frequently occurs in the context of a primary relationship between two partners; however, HIV prevention interventions generally focus on individuals at risk, rather than specifying...
Individual patient data meta-analysis of randomized controlled trials of dual therapy with a boosted PI plus lamivudine for maintenance of virological suppression: GeSIDA study 9717
Background: Dual therapy (DT) with a ritonavir-boosted PI (PI/r) plus lamivudine has proven non-inferior (12% margin) to triple therapy (TT) with PI/r plus two nucleos(t)ide reverse transcriptase inhibitors [N(t)RTIs] in...
Behavioral and cognitive interventions to improve treatment adherence and access to HIV care among older adults in sub-Saharan Africa: An updated systematic review
BACKGROUND: Approximately 14% of Africans infected with HIV are over the age of 50, yet few intervention studies focus on improving access to care, retention in care, and adherence to...
The effect of mental health issues on sexual risk behaviours and antiretroviral medication adherence among men who have sex with men
Key take-home messages Men who have sex with men and other sexual minorities may experience mental health problems that are rooted in sexual minority stress. Multiple mental health problems can...
Effectiveness of short message services and voice call interventions for antiretroviral therapy adherence and other outcomes: A systematic review and meta-analysis
BACKGROUND: The potential of using mobile phone technologies to improve antiretroviral therapy (ART) adherence has provided a new facet to human immunodeficiency virus (HIV) research. The quality of evidence and...
Is alcohol use associated with increased risk of developing adverse health outcomes among adults living with human immunodeficiency virus: A systematic review
BACKGROUND: Alcohol use is associated with many HIV-related behaviors that are associated with increased risk of reinfection, transmission, and poorer health outcomes in people living with HIV (PLHIV). The population...
The effect of alcohol consumption on ART adherence and sexual risk behaviours among men who have sex with men
Key take-home messages Among people living with HIV, alcohol consumption can have an impact on viral load and CD4 counts and affect adherence to antiretroviral regimens. Many studies have found...