Category Archives: Treatment

Climate change and HIV prevention: Towards sustainable solutions—A narrative review

2025

Climate change, with its pervasive environmental, social, and economic impacts, is emerging as a significant factor influencing global health outcomes, including the prevention and management of HIV. The intersection of...

Adherence definitions, measurement modalities, and psychometric properties in HIV, diabetes, and nutritional supplementation studies: A scoping review

2025

Measuring adherence has been a priority for researchers to help inform effective care for patients regularly consuming medications for chronic conditions. As a widely accepted “gold standard” adherence measure or...

Non-pharmacological interventions addressing chronic pain in people living with HIV

2025

PURPOSE OF REVIEW: Chronic pain affects 25-85% of people living with HIV (PLWH), negatively impacting health behaviors and HIV health outcomes. While opioids are frequently prescribed for pain, there are...

Impact of HIV-related stigma on antiretroviral therapy adherence, engagement and retention in HIV care, and transition to adult HIV care in pediatric and young adult populations living with HIV: A literature review

2024

Abstract HIV-related stigma is associated with negative effects on mental health and lower health-related quality of life in pediatric and young adult populations living with HIV. We reviewed literature on...

Lipid nanoparticles in antiretroviral therapy: A nanotechnology breakthrough for HIV/AIDS treatment

2025

BACKGROUND: The development of an effective drug delivery system for the treatment of HIV/AIDS is a global challenge. The conventional drug delivery approach, namely highly active antiretroviral therapy (HAART), has...

HIV associated motor neuron disease (MND): A case series with systematic review of literature

2025

Human immunodeficiency virus (HIV) associated motor neuron disease (MND) is very rare. HIV infection can cause an MND-like syndrome due to central nervous system (CNS) involvement de novo or during...

Bridging the gap: Identifying barriers and strategies for widespread implementation of long-acting injectable antiretroviral therapy in Sub-Saharan Africa: A scoping review

2025

BACKGROUND: Long-acting injectable antiretroviral therapy (LAI ART) is a new, and innovative approach to HIV treatment, designed to address several challenges, including the adherence issues associated with daily oral ART....

The global prevalence and impact of steatotic liver disease and viral infections: A systematic review and meta-analysis

2025

Background: Steatotic liver disease (SLD) affects ~30% of adults worldwide. The global population is continuously threatened by epidemic and endemic viral diseases. This study aims to thoroughly examine the interaction...

Barriers and facilitators to accessing sexual and reproductive health services for people with severe mental illness: A systematic review

2025

PURPOSE: Despite increased prevalence of sexual and reproductive health problems among people with severe mental illness (SMI), uptake of sexual and reproductive healthcare in this group is poor. The reasons...

Does climate change threaten delivery of HIV care in resource-limited settings?

2025

PURPOSE OF REVIEW: Extreme weather events (EWEs) pose a challenge to achieving UNAIDS goal of eliminating HIV as a public health threat by 2030. This review summarizes recent findings describing...

Preventing unintended pregnancies and HIV through self-care interventions in east and southern Africa: Findings from a structured review

2025

OBJECTIVE: To identify promising interventions targeting young people in East and Southern Africa through self-care practices, with a focus on prevention of unintended pregnancies and HIV and develop four evidence-based...

Satisfaction with HIV/AIDS treatment and care services and its associated factors among adult people receiving antiretroviral therapy in Ethiopia: A systematic review and meta-analysis

2025

Objective To make healthcare programmes more patient-centred and efficient in light of limited resources, it is crucial to ensure patient satisfaction. There is limited information on the overall level of...

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