Category Archives: Treatment

Knowledge of HIV and related best practices among non-HIV specific health care providers

2015

Key take-home messages One Canadian and several U.S. surveys have consistently shown a lack of HIV-related knowledge, awareness of HIV-related guidelines, and failure to screen for HIV among non-HIV specific...

Virologic failure and HIV drug resistance on simplified, dolutegravir-based maintenance therapy: Systematic review and meta-analysis

2018

Background: Dolutegravir-containing maintenance therapy is a promising simplification strategy for virologically suppressed HIV-infected individuals. However, most of the available data to inform this strategy come from small, uncontrolled studies. We...

Organ-specific toxicities due to radiation therapy in cancer patients with or without HIV infection: A systematic review of the literature

2018

Background: To synthesize published literature on the association between human immunodeficiency virus (HIV) infection and radiation therapy (RT)-related toxicities. Methods: Two electronic databases, MEDLINE and Embase, were searched to identify...

Models of outpatient care for the ongoing care and treatment of people living with HIV

2011

Key take-home messages Integrated care programmes that incorporate outpatient care, social support, psychosocial interventions and case management provide the best care for people with HIV. Accessible outpatient care can have...

The role of nurse practitioners in HIV care

2016

Key take-home messages Nurses are playing an increasing important role as people diagnosed with HIV live longer. HIV care provided by nurse practitioners is equal to or better than care...

Psychosocial and behavioural interventions towards HIV risk reduction for serodiscordant couples in Africa: A systematic review

2018

Background: Sexual transmission of HIV frequently occurs in the context of a primary relationship between two partners; however, HIV prevention interventions generally focus on individuals at risk, rather than specifying...

Individual patient data meta-analysis of randomized controlled trials of dual therapy with a boosted PI plus lamivudine for maintenance of virological suppression: GeSIDA study 9717

2018

Background: Dual therapy (DT) with a ritonavir-boosted PI (PI/r) plus lamivudine has proven non-inferior (12% margin) to triple therapy (TT) with PI/r plus two nucleos(t)ide reverse transcriptase inhibitors [N(t)RTIs] in...

Sexual abstinence among people living with HIV/AIDS

2011

Key take-home messages Diagnosis of HIV infection can have far-reaching implications: people’s sexual interest, the pleasure they derive from sex, their sense of attractiveness or appeal as a sexual partner...

Impact of successful hepatitis C treatment on quality of life

2016

Key take-home messages People living with HCV who receive treatment and achieve sustained virologic response (SVR) have better healthrelated quality of life scores than people who do not respond to...

Breast cancer and HIV in Sub-Saharan Africa: A complex relationship

2017

INTRODUCTION: The number and lifespan of individuals living with HIV have increased significantly with the scale-up of antiretroviral therapy. Furthermore, the incidence of breast cancer in women with HIV is...

Behavioral and cognitive interventions to improve treatment adherence and access to HIV care among older adults in sub-Saharan Africa: An updated systematic review

2018

BACKGROUND: Approximately 14% of Africans infected with HIV are over the age of 50, yet few intervention studies focus on improving access to care, retention in care, and adherence to...

East and South East Asian women’s sexual health

2012

Key take-home messages There is very little research that exclusively focuses on the sexual health and prevention of sexually transmitted infections (STIs) and/or HIV prevention for East and South East...

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