Category Archives: Treatment
Knowledge of HIV and related best practices among non-HIV specific health care providers
Key take-home messages One Canadian and several U.S. surveys have consistently shown a lack of HIV-related knowledge, awareness of HIV-related guidelines, and failure to screen for HIV among non-HIV specific...
Virologic failure and HIV drug resistance on simplified, dolutegravir-based maintenance therapy: Systematic review and meta-analysis
Background: Dolutegravir-containing maintenance therapy is a promising simplification strategy for virologically suppressed HIV-infected individuals. However, most of the available data to inform this strategy come from small, uncontrolled studies. We...
Organ-specific toxicities due to radiation therapy in cancer patients with or without HIV infection: A systematic review of the literature
Background: To synthesize published literature on the association between human immunodeficiency virus (HIV) infection and radiation therapy (RT)-related toxicities. Methods: Two electronic databases, MEDLINE and Embase, were searched to identify...
Models of outpatient care for the ongoing care and treatment of people living with HIV
Key take-home messages Integrated care programmes that incorporate outpatient care, social support, psychosocial interventions and case management provide the best care for people with HIV. Accessible outpatient care can have...
Psychosocial and behavioural interventions towards HIV risk reduction for serodiscordant couples in Africa: A systematic review
Background: Sexual transmission of HIV frequently occurs in the context of a primary relationship between two partners; however, HIV prevention interventions generally focus on individuals at risk, rather than specifying...
Individual patient data meta-analysis of randomized controlled trials of dual therapy with a boosted PI plus lamivudine for maintenance of virological suppression: GeSIDA study 9717
Background: Dual therapy (DT) with a ritonavir-boosted PI (PI/r) plus lamivudine has proven non-inferior (12% margin) to triple therapy (TT) with PI/r plus two nucleos(t)ide reverse transcriptase inhibitors [N(t)RTIs] in...
Behavioral and cognitive interventions to improve treatment adherence and access to HIV care among older adults in sub-Saharan Africa: An updated systematic review
BACKGROUND: Approximately 14% of Africans infected with HIV are over the age of 50, yet few intervention studies focus on improving access to care, retention in care, and adherence to...
