Category Archives: Treatment

Impact of SMS/GPRS printers in reducing time to early infant diagnosis compared to routine result reporting: A systematic review and meta-analysis

2017

BACKGROUND: Despite significant gains made towards improving access, early infant diagnosis (EID) testing programs suffer from long test turnaround times that result in substantial loss to follow-up and mortality associated...

Renal manifestations of HIV during the antiretroviral era in South Africa: A systematic scoping review

2017

BACKGROUND: It is estimated that 650,000 patients may develop human immunodeficiency virus (HIV)-related renal disease in South Africa. South Africa has recently adopted WHO policy, stipulating that all HIV-infected patients...

Evaluating the effectiveness of physical exercise interventions in persons living with HIV: Overview of systematic reviews

2017

Physical exercise (PE) has not been well studied in persons living with HIV (PLHIV). We conducted an overview of systematic reviews to assess the effectiveness of PE and to determine...

Zidovudine/lamivudine vs. abacavir/lamivudine vs. tenofovir/emtricitabine in fixed-dose combinations as initial treatment for HIV patients: A systematic review and network meta-analysis

2017

INTRODUCTION: Initial treatment of the HIV is based on the use of three drugs, two of which are nucleoside analog reverse-transcriptase inhibitors. There are three combinations of these drugs which...

Effectiveness of n-3 fatty acids in the treatment of hypertriglyceridemia in HIV/AIDS patients: A meta-analysis

2017

Hypertriglyceridemia is common in antiretroviral therapy-treated patients and Omega 3 fatty acids are being used as a intervention in reducing serum triglycerides (TG) in these patients. The objective of this...

Recent mobile health interventions to support medication adherence among HIV-positive MSM

2017

PURPOSE OF REVIEW: We describe recent mobile health (mHealth) interventions supporting antiretroviral therapy (ART) medication adherence among HIV-positive MSM. RECENT FINDINGS: Keyword searches (1 January 2016-13 May 2017) identified 721...

HIV and the criminalisation of drug use among people who inject drugs: A systematic review

2017

BACKGROUND: Mounting evidence suggests that laws and policies prohibiting illegal drug use could have a central role in shaping health outcomes among people who inject drugs (PWID). To date, no...

Objective impairments of gait and balance in adults living with HIV-1 infection: A systematic review and meta-analysis of observational studies

2017

BACKGROUND: Gait and balance deficits are reported in adults with HIV infection and are associated with reduced quality of life. Current research suggests an increased fall-incidence in this population, with...

Efficacy and tolerability of tenofovir disoproxil fumarate based regimen as compared to zidovudine based regimens: A systematic review and meta-analysis

2017

BACKGROUND: Although tenofovir (TDF)/emtricitabine (FTC)/efavirenz (EFV) and zidovudine (ZDV)/lamivudine (3TC)/efavirenz (EFV) are used as preferred first line regimen, their head-to-head comparison in terms of their efficacy and tolerability was limited....

HIV programs in Iran (Persia), Iraq and Saudi Arabia: A brief review of current evidence in West and Southwest Asia

2016

BACKGROUND: In Western and Southwest Asia, literature is not documented on human immunodeficiency virus (HIV) programs in Iran, Iraq and Saudi Arabia. The present study is the first brief review...

Nucleoside reverse transcriptase inhibitor-reducing strategies in HIV treatment: Assessing the evidence

2017

Antiretroviral (ARV) therapy, comprising a backbone of two nucleos(t)ide reverse transcriptase inhibitors (NRTIs) plus another ARV, is the recognized standard of care (SOC), which has helped extend life expectancy in...

Integration of sexually transmitted infection (STI) services into HIV care and treatment services for women living with HIV: A systematic review

2017

OBJECTIVE: To review and critically appraise the existing evidence on integration of sexually transmitted infection (STI) services into HIV care and treatment services for women living with HIV. DESIGN: Systematic...

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