Category Archives: Treatment
Efficacy and safety of atazanavir/ritonavir-based antiretroviral therapy for HIV-1 infected subjects: A systematic review and meta-analysis
Atazanavir (ATZ) is a well-tolerated protease inhibitor that can be boosted with ritonavir (r) to treat infection with resistant strains of human immunodeficiency virus 1 (HIV-1). The aim of this...
Incidence and prevalence of type 2 diabetes mellitus with HIV infection in Africa: A systematic review and meta-analysis
OBJECTIVES: This systematic review aims to investigate the incidence and prevalence of type 2 diabetes mellitus (T2DM) in patients with HIV infection in African populations. SETTING: Only studies reporting data...
A systematic review of patients’ perspectives on the subcutaneous route of medication administration
BACKGROUND: Subcutaneous injections allow for self-administration, but consideration of patients’ perspectives on treatment choice is important to ensure adherence. Previous systematic reviews have been limited in their scope for assessing...
Significant association between perceived HIV related stigma and late presentation for HIV/AIDS care in low and middle-income countries: A systematic review and meta-analysis
BACKGROUND: Late presentation for human immunodeficiency virus (HIV) care is a major impediment for the success of antiretroviral therapy (ART) outcomes. The role that stigma plays as a potential barrier...
The family’s role as a support network for people living with HIV/AIDS: A review of Brazilian research into the theme
The study of HIV transmission and the implementation of AIDS prevention actions recognize the importance of social networks in the transmission of the disease, the adherence to treatment and the...
Factors associated with hospitalizations among HIV-infected adults in the United States: Review of the literature
Although improving health outcomes in human immunodeficiency virus (HIV)-infected persons has been identified as a national priority, little is known about the factors associated with hospitalizations of HIV-infected persons in...
Pneumococcal conjugate vaccine in HIV-infected and HIV-exposed, uninfected children
INTRODUCTION: Incidence of invasive pneumococcal disease (IPD) among HIV-infected children is 20-40 fold greater compared to HIV-uninfected children, including among HIV-infected children on antiretroviral therapy (ART). Also, HIV-exposed, uninfected children...
Behavioural disinhibition in the general population during the antiretroviral therapy roll-out in Sub-Saharan Africa: Systematic review and meta-analysis
Objectives: Improved life expectancy and reduced transmission probabilities due to ART may result in behavioural disinhibition – that is an increase in sexual risk behaviour in response to a perceived lower...
Systematic review of sex work interventions in sub-Saharan Africa: Examining combination prevention approaches
OBJECTIVE: The incidence of HIV and sexually transmitted infections is disproportionately high among sex workers (SW). We aimed to update the evidence on the effectiveness of SW interventions in sub-Saharan...