Category Archives: Treatment

HIV and the criminalisation of drug use among people who inject drugs: A systematic review

2017

BACKGROUND: Mounting evidence suggests that laws and policies prohibiting illegal drug use could have a central role in shaping health outcomes among people who inject drugs (PWID). To date, no...

Objective impairments of gait and balance in adults living with HIV-1 infection: A systematic review and meta-analysis of observational studies

2017

BACKGROUND: Gait and balance deficits are reported in adults with HIV infection and are associated with reduced quality of life. Current research suggests an increased fall-incidence in this population, with...

Efficacy and tolerability of tenofovir disoproxil fumarate based regimen as compared to zidovudine based regimens: A systematic review and meta-analysis

2017

BACKGROUND: Although tenofovir (TDF)/emtricitabine (FTC)/efavirenz (EFV) and zidovudine (ZDV)/lamivudine (3TC)/efavirenz (EFV) are used as preferred first line regimen, their head-to-head comparison in terms of their efficacy and tolerability was limited....

HIV programs in Iran (Persia), Iraq and Saudi Arabia: A brief review of current evidence in West and Southwest Asia

2016

BACKGROUND: In Western and Southwest Asia, literature is not documented on human immunodeficiency virus (HIV) programs in Iran, Iraq and Saudi Arabia. The present study is the first brief review...

Nucleoside reverse transcriptase inhibitor-reducing strategies in HIV treatment: Assessing the evidence

2017

Antiretroviral (ARV) therapy, comprising a backbone of two nucleos(t)ide reverse transcriptase inhibitors (NRTIs) plus another ARV, is the recognized standard of care (SOC), which has helped extend life expectancy in...

Integration of sexually transmitted infection (STI) services into HIV care and treatment services for women living with HIV: A systematic review

2017

OBJECTIVE: To review and critically appraise the existing evidence on integration of sexually transmitted infection (STI) services into HIV care and treatment services for women living with HIV. DESIGN: Systematic...

Exploring ‘generative mechanisms’ of the antiretroviral adherence club intervention using the realist approach: A scoping review of research-based antiretroviral treatment adherence theories

2017

BACKGROUND: Poor retention in care and non-adherence to antiretroviral therapy (ART) continue to undermine the success of HIV treatment and care programmes across the world. There is a growing recognition...

Review of HIV treatment progress, gaps, and challenges in the Caribbean, 2005-2015

2016

Objective: To highlight the current context of the HIV response in the Caribbean and what remains to be addressed to close gaps in HIV treatment and care and end AIDS...

The impact of motivational interviewing on adherence and symptom severity in adolescents and young adults with chronic illness: A systematic review

2017

OBJECTIVE: Given the negative consequences associated with non-adherence in adolescents and young adults (AYAs) with chronic illness, it is important to identify interventions to address this issue. Therefore, this review’s...

Are religion and spirituality barriers or facilitators to treatment for HIV: A systematic review of the literature

2017

Much attention has been given to the relationship between religion/spirituality (R/S) and HIV in recent years, but comparatively little has been explored in regard to R/S and HIV testing, retention...

The association between HIV (treatment), pregnancy serum lipid concentrations and pregnancy outcomes: A systematic review

2017

BACKGROUND: Observed adverse effects of antiretroviral therapy (ART) on the lipid profile could be of significance in pregnancy. This systematic review aims to summarize studies that investigated the association between...

Reliability of white matter microstructural changes in HIV infection: Meta-analysis and confirmation

2017

BACKGROUND: Diffusion tensor imaging has been widely used to measure HIV effects on white matter microarchitecture. While many authors have reported reduced fractional anisotropy and increased mean diffusivity in HIV,...

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