Category Archives: Engagement and Care Cascade
INSTIs-centered antiviral regimens for first-line treatment of HIV/AIDS: A network meta-analysis and cost-effectiveness analysis
OBJECTIVE: This study evaluates the efficacy, safety, and cost-effectiveness of INSTI-based antiretroviral regimens compared to the national standard first-line treatment EFV/3TC/TDF for HIV/AIDS in China. The aim is to guide...
Barriers to retention in care among adults with HIV in developed countries: An integrative review
Focusing on factors hindering viral suppression is essential for improving the health outcomes of people with Human Immunodeficiency Virus (HIV) and working towards ending the HIV/AIDS epidemic. The aim of...
Breast cancer clinical characteristics, management, and outcomes in women living with HIV/AIDS globally: A systematic review and meta-analysis
Although associations between HIV and breast cancer (BC) have been investigated, the global literature remains inconsistent regarding clinical features and outcomes in HIV-positive patients. This study aims to clarify the...
Perinatal outcomes among pregnant women with HIV initiating antiretroviral therapy preconception and antenatally
OBJECTIVE: Increasingly, pregnant women with HIV (WHIV) initiate antiretroviral therapy (ART) before conception. We assessed the risk of adverse perinatal outcomes among pregnant WHIV initiating ART preconception or antenatally, compared...
Clinical trials of broadly neutralizing monoclonal antibodies in people living with HIV—A review
Introduction HIV-1 remains a major global health challenge, impacting approximately 39 million people worldwide. Although antiretroviral therapy has substantially reduced HIV incidence and enhanced the quality of life for those living...
Experiences of older people living with human immunodeficiency virus comorbidity attending coordinated healthcare services
BACKGROUND: Older people living with human immunodeficiency virus (OPLWHIV) on antiretroviral therapy are aging and face an increased risk of non-communicable diseases. The burden is costly and demands sustainable care...
The role of digital tools in enhancing antiretroviral therapy adherence among adolescents and young adults with HIV: A systematic review of randomized controlled trials
Background: Adolescents and Young Adults (AYA) face challenges in maintaining antiretroviral therapy (ART) adherence, necessitating the need for targeted and innovative interventions. Digital tools have shown potential in improving ART adherence...
Insights into gastrointestinal manifestation of human immunodeficiency virus: A narrative review
Human immunodeficiency virus (HIV) modifies CD4-positive cells, resulting in immunodeficiency and a wide range of gastrointestinal (GI) manifestations. The burden of HIV-related GI illnesses has significantly evolved with the widespread...
An international compendium of health state utilities in people with HIV: A systematic review
Purpose: Measuring health-related quality of life across different health states for people with HIV (PWH) using direct or indirect preference-based values can inform decision-analytic models evaluating cost-effectiveness of different care strategies....
