Category Archives: Engagement and Care Cascade
Neuropsychiatric outcomes in children and adolescents with perinatally acquired HIV: A systematic review and meta analysis
Objective: The objective of this study is to define the neuropsychiatric challenges including developmental delay, cognitive impairment, and psychiatric illness faced by children with perinatally acquired HIV. Data sources: Nine databases were...
Breaking the silence—Systematic review of the socio-cultural underpinnings of men’s sexual and reproductive health in Middle East and North Africa (MENA): A handful of taboos?
BACKGROUND: Sociocultural aspects can impact sexual and reproductive health (SRH). Despite this, no study appraised the socio-cultural underpinnings impacting men’s SRH in MENA (Middle East and North Africa). The current...
HIV interventions across the care continuum for adolescents in high-burden countries: A systematic review and meta-analysis
BACKGROUND: Adolescents (10-19 years old) have poor outcomes across the prevention-to-treatment HIV care continuum, leading to significant mortality and morbidity. We conducted a systematic review and meta-analysis of interventions that...
Clinical events associated with poor CD4(+) T-cell recovery in people living with HIV following ART: A systematic review and meta-analysis
Background: Antiretroviral therapy (ART) has significantly improved outcomes for people living with HIV (PLWH), but poor CD4+ T-cell recovery remains a challenge. This study aimed to evaluate the relationship between poor CD4+ T-cell...
Enhancing HIV cognitive abilities and self-management through information technology-assisted interventions: Scoping review
BACKGROUND: HIV/AIDS remains a significant global challenge, and with the rapid advancement of technology, there has been an increasing number of interventions aimed at improving HIV/AIDS cognition and self-management behaviors...
Determinants of HIV pre-exposure prophylaxis (PrEP) use among men who have sex with men (MSM) living in rural areas of the United States: A scoping review framed by the PrEP care continuum
BACKGROUND: HIV pre-exposure prophylaxis (PrEP) is a highly effective intervention to prevent HIV transmission among men who have sex with men (MSM). Despite its effectiveness, PrEP uptake and adherence among...
Systematic review and meta-analysis of retention and disengagement after initiation on antiretroviral therapy in low- and middle-income countries after the introduction of universal test and treat policies
BACKGROUND: We previously published a systematic review evaluating retention in care after antiretroviral therapy treatment initiation among adults in low- and middle-income countries. We estimated retention at 36 months to...
Cardiovascular disease and its risk factors among people living with HIV: A systematic review and meta-analysis
This meta-analysis aimed to quantify the latest cardiovascular disease (CVD) incidence rate and assess the impact of risk factors among people living with HIV (PLWH). We searched PubMed, Embase, Web...
Prevalence of depression among people living with HIV on antiretroviral therapy in Africa: A systematic review and meta-analysis
BACKGROUND: HIV is a global health issue, with the highest number of infected individuals found in sub-Saharan Africa. The coexistence of HIV with depression is a huge challenge. This study...
Safety and efficacy of long-acting cabotegravir/rilpivirine versus standard oral antiretroviral therapy: A systematic review and meta-analysis
Background In 2023, there were 39.9 million people living with HIV (PLWH) worldwide and 630 000 deaths related to HIV. New strategies are needed, and long-acting antiretrovirals (LAAs) are now widely...
