Category Archives: Engagement and Care Cascade

Current trends and future directions in probiotics research for HIV/AIDS

2024

AIM: This study aims to comprehensively and systematically review the current status of research on probiotics and HIV/AIDS, while also exploring future research hotspots and trends in this domain. METHODS:...

Systematic review and meta-analysis of retention and disengagement after initiation on antiretroviral therapy in low- and middle-income countries after the introduction of universal test and treat policies

2024

BACKGROUND: We previously published a systematic review evaluating retention in care after antiretroviral therapy treatment initiation among adults in low- and middle-income countries. We estimated retention at 36 months to...

Cardiovascular disease and its risk factors among people living with HIV: A systematic review and meta-analysis

2025

This meta-analysis aimed to quantify the latest cardiovascular disease (CVD) incidence rate and assess the impact of risk factors among people living with HIV (PLWH). We searched PubMed, Embase, Web...

Prevalence of depression among people living with HIV on antiretroviral therapy in Africa: A systematic review and meta-analysis

2025

BACKGROUND: HIV is a global health issue, with the highest number of infected individuals found in sub-Saharan Africa. The coexistence of HIV with depression is a huge challenge. This study...

Safety and efficacy of long-acting cabotegravir/rilpivirine versus standard oral antiretroviral therapy: A systematic review and meta-analysis

2025

Background In 2023, there were 39.9 million people living with HIV (PLWH) worldwide and 630 000 deaths related to HIV. New strategies are needed, and long-acting antiretrovirals (LAAs) are now widely...

How does intersectionality impact the quality of healthcare services for Black women living with HIV?

2024

Women with HIV are affected more than men by intersecting discriminations. For Black women, additional discrimination can have a detrimental effect on their HIV care. An extended literature review of...

Prevalence of suicidal ideation and associated factors among perinatal women living with HIV: A systematic review and meta-analysis

2025

Perinatal women living with HIV face increased susceptibility to mental health challenges, including suicidal ideation (SI). This study aimed to determine the prevalence of SI among perinatal women with HIV...

A global review of national guidelines of post-exposure prophylaxis for the prevention of HIV

2025

INTRODUCTION: The World Health Organization (WHO) recommends the use of antiretroviral drugs as post-exposure prophylaxis (PEP) for preventing HIV acquisition for occupational and non-occupational exposures. To inform the development of...

Comparative efficacy of antifungal drugs for the treatment of oral candidiasis in HIV-positive patients: A Bayesian network meta-analysis

2024

Oral candidiasis infection is particularly prevalent among individuals in HIV-positive patients. Antifungal drugs have shown promising therapeutic effects in treating oral candidiasis in HIV-positive patients. However, the selection of specific...

Systematic review of reviews on interventions to engage men and boys as clients, partners and agents of change for improved sexual and reproductive health and rights

2025

OBJECTIVES: Evidence regarding interventions to engage men and boys to improve sexual and reproductive health and rights (SRHR) has grown rapidly across subtopics such as HIV, family planning and gender-based...

Determination of depression prevalence in pregnant women living with HIV aged 18 years and older: A meta-analysis study

2025

BACKGROUND: Pregnant women living with HIV are known to be at higher risk of depression than pregnant women without HIV. Accompanied by a systematic literature review, the aim of this...

Additive effects of glutathione in improving antibiotic efficacy in HIV-M.tb co-Infection in the central nervous system: A systematic review

2025

BACKGROUND: HIV and tuberculosis (TB) co-infection poses a significant health challenge, particularly when involving the central nervous system (CNS), where it leads to severe morbidity and mortality. Current treatments face...

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