Category Archives: Engagement and Care Cascade

The prevalence of HIV-infected patients with virological suppression but a CD4+ T-cell count of ≤ 200 cells/mm3 after highly active antiretroviral therapy initiation: A meta-analysis

2022

Highly active antiretroviral therapy (HAART) strongly inhibits HIV replication. However, many patients show suboptimal immune recovery (SIR), as defined by virological suppression (i.e. low viral load) with a CD4+ T-cell count...

Factors associated with post-treatment control of viral load in HIV-infected patients: A systematic review and meta-analysis

2023

BACKGROUND: This study aimed to investigate the factors associated with maintenance of viral suppression after antiretroviral therapy (ART) discontinuation. METHODS: Databases were searched for studies published between 1 January, 2011,...

Perinatal outcomes associated with combination antiretroviral therapy compared with monotherapy

2023

Objectives: Increasing numbers of women living with HIV (WLHIV) worldwide receive combination antiretroviral therapy (cART) during pregnancy. We aimed to assess the risk of adverse perinatal outcomes in pregnant WLHIV receiving...

Mental health problems across the HIV care continuum for adolescents living with HIV in sub-Saharan Africa: A scoping review

2023

Mental health problems (e.g., anxiety, depression) are frequently experienced by adolescents living with HIV (ALWH) and can worsen HIV-related outcomes. This scoping review synthesizes the existing research on ALWHs’ mental...

Universal health coverage for antiretroviral treatment: A review

2023

Universal health coverage is essential for the progress to end threats of the acquired immunodeficiency syndrome epidemic. The current review assesses the publication rate, strategies and barriers for antiretroviral therapy...

Virological failure and adherence to antiretroviral therapy in adolescents and young adults living with human immunodeficiency virus

2023

Objective: HIV (human immunodeficiency virus) infection remains a major public health challenge. Infected young people at any age are less likely to adhere to care in a timely manner and to...

Digital directly observed therapy to monitor adherence to medications: A scoping review

2022

Background: Technology-based directly observed therapy (DOT) is more cost-effective and efficient compared with in-person monitoring visits for medication adherence. While some evidence shows these technologies are feasible and acceptable, there...

Digital sexually transmitted infection and HIV services across prevention and care continuums: Evidence and practical resources

2022

Increased demand for sexual health services (including prevention and treatment) have spurred the development of digital STI/HIV services. Earlier advances in testing technologies opened the door for self-testing and self-sampling...

Leveraging resilience-supportive strategies to enhance protective factors in young sexual minority men: A scoping review of HIV behavioral interventions implemented in high-income countries

2022

Behavioral HIV interventions focused on strengthening young sexual minority men’s (SMM) internal (assets) and external (resources) protective factors are promising, yet their evaluation as resilience-supportive strategies to minimize or negate...

What is polypharmacy in people living with HIV/AIDS? A systematic review

2022

Polypharmacy in people living with HIV/AIDS (PLWHA) is a rising morbidity that exacts hefty economic burden on health budgets in addition to other adverse clinical outcomes. Despite recent advances, uncertainty...

Impact of the COVID-19 pandemic on HIV healthcare service engagement, treatment adherence, and viral suppression in the United States: A systematic literature review

2022

The COVID-19 pandemic has necessitated adaptations in how healthcare services are rendered. However, it is unclear how these adaptations have impacted HIV healthcare services across the United States. We conducted...

Health-related needs reported by adolescents living with HIV and receiving antiretroviral therapy in sub-Saharan Africa: A systematic literature review

2022

INTRODUCTION: Adolescents living with HIV (ALHIV) on antiretroviral therapy (ART) have specific health needs that can be challenging to deliver. Sub-Saharan Africa (SSA) is home to 84% of the global...

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