Category Archives: Engagement and Care Cascade
Efficacy and safety of systematic corticosteroids treatment among patients with HIV and tuberculosis: A systematic review and meta-analysis of randomized controlled trials
INTRODUCTION: The efficacy and safety of corticosteroids in patients with human immunodeficiency virus (HIV) and tuberculosis (TB) remain controversial. METHOD: PubMed, Embase, Web of Science, and the Cochrane Database were...
Prevalence of HIV drug resistance among patients experiencing first-line treatment failure in Ethiopia: A systematic review and meta-analysis
Background The emergence of human immunodefiency virus (HIV) drug resistance presents a substantial challenge. Alternatives for effective treatment regimens are limited, and treatment strategies are complicated. Although a number of...
Measuring mobility in HIV research in sub-Saharan Africa: A scoping review
INTRODUCTION: Mobility-from overnight travel to permanent migration-can reduce service access and increase HIV risk, driving the epidemic in sub-Saharan Africa (SSA). This scoping review described mobility measures used in HIV...
Association between antiretroviral therapy and dental caries in children and adolescents with HIV: A systematic review and meta-analysis
OBJECTIVE: To evaluate the evidenceAÿregarding the association between antiretroviral therapy and dental caries in children and adolescents with HIV. METHODS: Searches were conducted in five international databases (PubMed, Scopus, EMBASE,...
The association between disclosure and antiretroviral therapy among adults living with HIV in China: A systematic review and meta-analysis
Background Antiretroviral therapy (ART) and ART adherence are crucial for preventing HIV transmission and prolonging the lifespan of people living with HIV (PLWH). Serostatus disclosure is a significant factor influencing...
Comparison of treatment-emergent resistance-associated mutations and discontinuation due to adverse events among integrase strand transfer inhibitor-based single-tablet regimens and cabotegravir + rilpivirine for the treatment of virologically suppressed people with HIV: A systematic literature review and network meta-analysis
Objective This study evaluated rates of treatment‐emergent resistance‐associated mutations (TE‐RAMs) and discontinuation due to adverse events (DC‐AEs) across integrase strand transfer inhibitor (INSTI)‐based single‐tablet regimens and injectable cabotegravir + rilpivirine...
HIV-1 drug resistance in children and implications for pediatric treatment strategies: A systematic review and meta-analysis
Introduction Failure in the prevention of mother-to-child HIV transmission (PMTCT) and pediatric treatment challenges led to pretreatment drug resistance (PDR) and acquired drug resistance (ADR) in children with HIV (CWHIV)....
The association between HIV infection and carotid intima-media thickness in the era of antiretroviral therapy: A meta-analysis
Atherosclerosis remains a leading cause of mortality globally, and this is worse in people living with HIV (PLHIV). While the administration of antiretroviral therapy (ART) in this population has significant...
HIV infection and antiretroviral therapy impair liver function in people living with HIV: Systematic review and meta-analysis
Background: The use of antiretroviral therapy (ART) has improved the lives of people living with HIV (PLWH). However, its use is associated with secondary complications, notably hepatotoxicity. This systematic review and...
Retention in HIV care among Southeast Asian people living with HIV: A systematic review and meta-analysis
Background Despite the effectiveness of antiretroviral therapy (ART) in reducing HIV-related morbidity and mortality, the retention of HIV care remains suboptimal in Southeast Asia. Objective This systematic review and meta-analysis...