Category Archives: Engagement and Care Cascade
Adherence to option B+ and its association with disclosure status and counseling among HIV-positive pregnant and lactating women in Ethiopia: Systematic review and meta-analysis
Objectives: This systematic review and meta-analysis aimed to assess the pooled estimate of option B+ level of adherence and its association with disclosure status and counseling among pregnant and lactation women...
Prevalence and global trends of polypharmacy among people living with HIV: A systematic review and meta-analysis
Background: There has been a rising prevalence of polypharmacy among people living with HIV (PLWH). Uncertainty however remains regarding the exact estimates of polypharmacy among these cohorts of patients. Methods: We conducted...
Ingestible electronic sensors for monitoring real-time adherence to HIV pre-exposure prophylaxis and antiretroviral therapy
PURPOSE OF REVIEW: This review summarizes the recent advancements and future directions of digital pill systems (DPS) – which utilize ingestible sensors to directly measure medication ingestion events in real-time...
Linkage to HIV care following HIV self-testing among men: Systematic review of quantitative and qualitative studies from six countries in sub-Saharan Africa
Gender disparities are pervasive throughout the HIV care continuum in sub-Saharan Africa, with men testing, receiving treatment, and achieving viral suppression at lower rates, and experiencing mortality at higher rates,...
Economic benefits of the United States’ AIDS drug assistance program: A systematic review of cost analyses to guide research and policy priorities
As part of the Ryan White HIV/AIDs Program, the federally-funded, state-administered AIDS Drug Assistance Program (ADAP) provides prescription drug medications, including antiretroviral therapy, for people with HIV (PWH) who are...
Storyboarding HIV infected young people’s adherence to antiretroviral therapy in lower- to upper middle-income countries: A new-materialist qualitative evidence synthesis
Young people living with perinatal infections of Human Immunodeficiency Virus (YLPHIV) face a chronic disease, with treatment including adherence to lifelong antiretroviral treatment (ART). The aim of this QES was...
Men who have sex with men is the high-risk drug resistance population: A meta-analysis of HIV-1 drug resistance profiles and trends in China
WHAT IS KNOWN AND OBJECTIVE: Except for the transmitted drug resistance (TDR)’s standard sampling and monitoring protocol, China’s HIV-1 pretreatment drug resistance (PDR) and acquired drug resistance (ADR) results vary...
Evaluating the impact of the COVID-19 pandemic on accessing HIV services in South Africa: A systematic review
Progress has been made towards controlling the Human Immunodeficiency Virus (HIV) epidemic in South Africa. However, the emergence of coronavirus disease 2019 (COVID-19) has disrupted access to health care. This...
Pre-treatment HIV-1 drug resistance in antiretroviral therapy-naive adults in Eastern Africa: A systematic review and meta-analysis
Background: Pre-treatment HIV drug resistance (PDR) may result in increased risk of virological failure and acquisition of new resistance mutations. With recently increasing ART coverage and periodic modifications of the guidelines...
How mHealth can contribute to improving the continuum of care: A scoping review approach to the case of human immunodeficiency virus in sub-Saharan Africa
Objectives: To determine mHealth’s contribution to improving the continuum of care in sub-Saharan Africa towards achieving treatment targets for human immunodeficiency virus (HIV) endorsed by the 2016 Political Declaration on...
A systematic review of digital interventions to improve ART adherence among youth living with HIV in sub-Saharan Africa
An estimated 3.4 million youth aged 15–24 years live with human immunodeficiency virus (HIV), a majority of whom reside in sub-Saharan Africa (SSA). Youth living with HIV (YLHIV) generally maintain...
