Shared immunotherapeutic approaches in HIV and hepatitis B virus: Combine and conquer
2020
PURPOSE OF REVIEW: The aim of this study was to identify similarities, differences and lessons to be shared from recent progress in HIV and hepatitis B virus (HBV) immunotherapeutic approaches....
Challenges and opportunities for hepatitis B cure in the setting of HIV–Hepatitis B virus co-infection
2020
PURPOSE OF REVIEW: To examine issues specific to HIV–HBV co-infection that are relevant to the search for and achieving hepatitis B cure in this the setting RECENT FINDINGS: In HIV–HBV...
Enhancing care for people living with HIV: Current and future monitoring approaches
2021
INTRODUCTION: Antiretroviral therapy (ART) is the most significant advance in the medical management of HIV-1 infection. Given the fact that HIV cannot be eradicated from the body, ART has to...
Adolescents and young adults with early acquired HIV infection in the United States: Unique challenges in treatment and secondary prevention
2021
INTRODUCTION: Worldwide, children who acquired human immunodeficiency virus (HIV) at an early age, either perinatally or through blood transfusion, are reaching adolescence and adulthood due to successful antiretroviral treatment (ART)....
Efavirenz versus protease inhibitors in patients with HIV: A systematic review and meta-analysis
2021
Efavirenz- and protease inhibitor (PI)-based regimens remain viable options across the globe. We conducted a meta-analysis to compare the effectiveness of efavirenz-based regimens relative to PI-based regimens. EMBASE, PubMed, Cochrane,...
Low inducibility of latent human immunodeficiency virus type 1 proviruses as a major barrier to cure
2021
The latent reservoir for human immunodeficiency virus type 1 (HIV-1) in resting CD4+ T cells is a major barrier to cure. The dimensions of the reservoir problem can be defined...
1,2,3-Triazole hybrids with anti-HIV-1 activity
2021
The human immunodeficiency virus type 1 (HIV-1) is the major etiological agent responsible for the acquired immunodeficiency syndrome (AIDS), which is a serious infectious disease and remains one of the...
Differences in outcomes of chemoradiation in women with invasive cervical cancer by human immunodeficiency virus status: A systematic review
2021
PURPOSE: Cervical cancer is one of the leading causes of cancer death among women worldwide, and women living with human immunodeficiency virus (HIV) carry the highest burden of disease. Chemoradiation...
A review of potential microbiome-gut-brain axis mediated neurocognitive conditions in persons living with HIV
2020
The microbiome-gut-brain axis, or the various interactions between the gut microbiome and the brain, has been of recent interest in the context of precision medicine research for a variety of...
Recommendations for increasing physician provision of pre-exposure prophylaxis: Implications for medical student training
2021
There is growing evidence that pre-exposure prophylaxis (PrEP) prevents HIV acquisition. However, in the United States, approximately only 4% of people who could benefit from PrEP are currently receiving it,...
The role of oxidative stress in HIV-associated neurocognitive disorders
2021
HIV-associated neurocognitive disorders (HAND) are a leading cause of morbidity in up to 50% of individuals living with HIV, despite effective treatment with antiretroviral therapy (ART). Current evidence suggests that...
What’s new in bone disease and fractures in HIV?
2021
PURPOSE OF REVIEW: People living with HIV (PWH) are at greater risk of low bone mineral density (BMD) and fractures compared to the general population. This narrative review summarises recent...
