Category Archives: Engagement and Care Cascade
Microbiota-meditated immunity abnormalities facilitate hepatitis B virus co-infection in people living with HIV: A review
Hepatitis B virus (HBV) co-infection is fairly common in people living with HIV (PLWH) and affects millions of people worldwide. Identical transmission routes and HIV-induced immune suppression have been assumed...
Drug-drug interactions in people living with HIV at risk of hepatic and renal impairment: Current status and future perspectives
Despite the advancement of antiretroviral therapy (ART) for the treatment of human immunodeficiency virus (HIV), drug-drug interactions (DDIs) remain a relevant clinical issue for people living with HIV receiving ART....
Community-based ART service delivery for key populations in sub-Saharan Africa: Scoping review of outcomes along the continuum of HIV care
HIV positive key population (KP) often face health system and social barriers to HIV care. KP include sex workers, men who have sex with men, persons who inject drugs, transgender...
Strategies to improve HIV care outcomes for people with HIV who are out of care: a meta-analysis
Objective: The aim of this study was to evaluate the effectiveness of five intervention strategies: patient navigation, appointment help/alerts, psychosocial support, transportation/appointment accompaniment, and data-to-care on HIV care outcomes among persons...
Impact of combined antiretroviral therapy on metabolic syndrome components in adult people living with HIV: A literature review
The development of metabolic derangements as a result of HIV treatment has been an important area of research since the introduction of zidovudine in the 1980’s. Antiretroviral therapy has intensely...
Risk of vertical transmission of chronic viral infections after invasive prenatal procedures
OBJECTIVES: Invasive prenatal procedures including amniocentesis, chorionic villus sampling (CVS) can be prenatally indicated for diagnostic purposes. Chronic viral infections with Human Immunodeficiency Virus (HIV), hepatitis C virus (HCV), hepatitis...
SARS-CoV-2 infection and coronavirus disease 2019 severity in persons with HIV on antiretroviral treatment
The relative susceptibility of people with HIV (PWH) to Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection is debated. Numerous studies have been published with apparently contradictory findings, but comparisons...
Cost-effectiveness of HIV retention and re-engagement interventions in high-income countries: A systematic literature review
Engagement in lifelong HIV care is critical for both patient and public health, yet there are limited resources to invest in improving HIV outcomes. We systematically reviewed evidence on the...
Safety of antiretroviral therapy in the treatment of HIV/AIDS in children: Systematic review and meta-analysis
The safety of using different antiretroviral therapies (ART) in pediatric HIV/AIDS patients is not well-established. Therefore, this study aimed to assess the safety of ART in children. A systematic review...
Population sizes, HIV prevalence, and HIV prevention among men who paid for sex in sub-Saharan Africa (2000–2020): A meta-analysis of 87 population-based surveys
BACKGROUND: Key populations, including sex workers, are at high risk of HIV acquisition and transmission. Men who pay for sex can contribute to HIV transmission through sexual relationships with both...
