Category Archives: Engagement and Care Cascade
A mega-aggregation framework synthesis of the barriers and facilitators to linkage, adherence to ART and retention in care among people living with HIV
BACKGROUND: People living with human immunodeficiency virus (PLHIV) struggle with the challenges of living with a chronic disease and integrating antiretroviral treatment (ART) and care into their daily lives. The...
Barriers to the management of children under five exposed to HIV in the rural areas of South Africa
BACKGROUND: South Africa has made enormous progress in reducing mother-to-child transmission (MTCT) of human immunodeficiency virus (HIV), however, MTCT and AIDS related death persist among children particularly in the rural...
A narrative systematic literature review: A focus on qualitative studies on HIV and medication-assisted therapy in the United States
Over the last two decades, the United States (U.S.) has experienced an opioid crisis that has had a significant negative societal and economic impact. Due to the high utilization of...
Neurotoxicities in the treatment of HIV between dolutegravir, rilpivirine and dolutegravir/rilpivirine: A meta-analysis
Objective: To assess the risk of neuropsychiatric adverse effects (ie, depression, anxiety, insomnia, dizziness, suicidal behaviour) among patients treated with rilpivirine, dolutegravir and dolutegravir/rilpivirine. Design: This is a systematic review and meta-analysis of...
Predictors of lost to follow up from antiretroviral therapy among adults in sub-Saharan Africa: A systematic review and meta-analysis
Background: It is known that ‘drop out’ from human immunodeficiency virus (HIV) treatment, the so called lost-to-follow-up (LTFU) occurs to persons enrolled in HIV care services. However, in sub-Saharan Africa (SSA),...
Adherence to HIV care and associated health functioning among youth living with HIV in Sub-Saharan Africa
Older adolescents and young adults (youth) living with HIV (YLH) in sub-Saharan Africa (SSA) are at high risk for poor HIV treatment adherence and associated negative health outcomes including viral...
Stigma, HIV risk, and access to HIV prevention and treatment services among me who have sex with mem (MSM) in the United States: A scoping review
In light of recent advances in HIV prevention and treatment, we reviewed the literature to understand how different types of stigma impact HIV risk; access to HIV prevention, care, and...
Systematic review and meta-analysis of treatment interruptions in human immunodeficiency virus (HIV) type 1-infected patients receiving antiretroviral therapy: Implications for future HIV cure trials
BACKGROUND: Safety and tolerability of analytical treatment interruptions (ATIs) as a vital part of human immunodeficiency virus type 1 (HIV-1) cure studies are discussed. We analyzed current evidence for the...
A review of reported cases of HIV pre-exposure prophylaxis failure with resultant breakthrough HIV infections
OBJECTIVES: Early randomized controlled trials (RCTs) have confirmed high efficacy of pre-exposure prophylaxis (PrEP) for preventing HIV infection in men who have sex with men (MSM) with high HIV exposure...
