Category Archives: Engagement and Care Cascade
Immunogenicity and safety of the booster COVID-19 vaccine among people with HIV: A systematic review and meta-analysis
Background Human immunodeficiency virus (HIV) and COVID-19 continue to pose significant global public health challenges. Although vaccination is essential for preventing COVID-19 in people with HIV (PWH), evidence on the...
Artificial intelligence for HIV care: A global systematic review of current studies and emerging trends
INTRODUCTION: Artificial intelligence (AI) and, in particular, machine learning (ML) have emerged as transformative tools in HIV care, driving advancements in diagnostics, treatment monitoring and patient management. The present review...
Hepatitis C increases acute myocardial infarction risk in people living with HIV: A systematic review and meta-analysis
BackgroundHepatitis C virus (HCV) coinfection is common among people living with HIV (PLWH) and is associated with adverse outcomes. However, the specific association between HCV coinfection and the risk of...
Performance of adherence measures for oral, tenofovir-based HIV pre-exposure prophylaxis: A systematic review
Accurate adherence measures to HIV pre-exposure prophylaxis (PrEP) are essential for identifying individuals with low adherence and providing tailored support. This systematic review summarizes evidence on the performance of PrEP...
Intermittent preventive treatment regimens for malaria in HIV-positive pregnant women: Systematic review and meta-analysis of clinical trials
Background: The WHO recommended the use of intermittent preventive treatment (IPT) regimens for malaria in HIV-positive pregnant women living in endemic areas to prevent malaria-related perinatal complications. However, the high drug...
Prevalence and factors associated with HIV viral rebound in individuals on ART: A systematic review study
BACKGROUND: Viral rebound (VR), the resurgence of detectable human immunodeficiency virus (HIV) viral loads (> 50 copies/mL) after suppression, remains a challenge for individuals on antiretroviral therapy (ART) in South...
Single-session interventions to enhance HIV outcomes among adolescents and young adults: A systematic scoping review and implications for integrating HIV and mental health services
Significant progress has been made in HIV prevention and treatment for adolescents and young adults (AYA), but integrating mental healthcare remains essential to address risks and improve treatment engagement. Single-session...
Probability of vertical HIV transmission: A systematic review and meta-regression
Background Eliminating HIV vertical transmission is a global priority and monitored by estimating paediatric HIV infections with the UNAIDS-supported Spectrum AIDS Impact Module (Spectrum-AIM). Recent innovations in antiretroviral therapy (ART)...
The impact of antiretroviral therapy (ART) on HPV persistence and cervical cancer progression among women with HPV/HIV co-infection: A systematic review
Cervical cancer remains the leading cause of cancer-related morbidity and mortality among women globally, particularly in low- and middle-income countries. Women living with HIV are at risk of persistent high-risk...
HIV infection is associated with accelerated epigenetic ageing: A systematic review
PURPOSE: We conducted a systematic review of studies comparing the intensity of epigenetic ageing in people living with human immunodeficiency virus (HIV) and uninfected individuals. We included studies that quantitatively...
State of HIV research in Venezuela: A systematic review
BACKGROUND: Venezuela’s recent economic and political instability has severely compromised its healthcare infrastructure, impacting the management of infectious diseases, including human immunodeficiency virus (HIV). This disruption hinders progress towards the...
