Category Archives: Engagement and Care Cascade
Meta-analysis of TB & HIV co-infection mortality rate in sub-Saharan African children, youth, and adolescents
Background Despite the effectiveness of antiretroviral treatment (ART) in reducing morbidity and mortality, children and adolescents with co-infections face an elevated risk of death due to their young age and...
HIV, hepatitis, and syphilis self-testing among adolescents and young adults: A systematic review and meta-analysis
Background: Adolescents and young adults (AYA) make up a significant share of the world’s burden of HIV and other sexually transmitted infections (STI). Self-testing can increase testing coverage and strengthen the...
Growth patterns of HIV-exposed and -unexposed infants in African countries: A systematic review and meta-analysis
Background/Objectives: The purpose of this study is to understand the prevalence and odds of poor growth patterns among HIV-exposed but uninfected (HEU) versus HIV-unexposed (HUU) infants in the era of antiretroviral...
HIV-1 drug resistance in children and implications for pediatric treatment strategies: A systematic review and meta-analysis
Introduction Failure in the prevention of mother-to-child HIV transmission (PMTCT) and pediatric treatment challenges led to pretreatment drug resistance (PDR) and acquired drug resistance (ADR) in children with HIV (CWHIV)....
HIV infection and antiretroviral therapy impair liver function in people living with HIV: Systematic review and meta-analysis
Background: The use of antiretroviral therapy (ART) has improved the lives of people living with HIV (PLWH). However, its use is associated with secondary complications, notably hepatotoxicity. This systematic review and...
The association between HIV infection and carotid intima-media thickness in the era of antiretroviral therapy: A meta-analysis
Atherosclerosis remains a leading cause of mortality globally, and this is worse in people living with HIV (PLHIV). While the administration of antiretroviral therapy (ART) in this population has significant...
Estimating the effect of maternal viral load on perinatal and postnatal HIV transmission: A systematic review and meta-analysis
Background Although a growing body of evidence supports zero risk of sexual HIV transmission from a person with sustained virological suppression, known as U=U (undetectable equals untransmittable), data have been...
Retention in HIV care among Southeast Asian people living with HIV: A systematic review and meta-analysis
Background Despite the effectiveness of antiretroviral therapy (ART) in reducing HIV-related morbidity and mortality, the retention of HIV care remains suboptimal in Southeast Asia. Objective This systematic review and meta-analysis...
Family influences on antiretroviral therapy adherence in youth with HIV in the United States: A systematic review
HIV poses a significant issue in the United States and understanding how HIV-positive populations adhere to treatments, specifically with antiretroviral therapy (ART), is vital for researchers to find approaches to...
Depression and associated factors among human immunodeficiency virus-positive pregnant women in sub-Saharan Africa: Systematic review and meta-analysis
BACKGROUND: Despite its severe impact on both maternal and fetal health, antenatal depression has not received as much attention in the healthcare community as postnatal depression. Comprehensive evidence is very...
