Category Archives: Engagement and Care Cascade
Older African Americans and the HIV care continuum: A systematic review of the literature, 2003-2018
Evidence suggests that racial disparities in the HIV care continuum persist in older age groups, particularly among African Americans. The objective of this systematic review was to identify factors that...
HIV, depression, and cognitive impairment in the era of effective antiretroviral therapy
PURPOSE OF REVIEW: Mental health disorders, especially depression, are prevalent among people living with HIV (PLWH) and are associated with cognitive impairment (CI) among HIV-uninfected (HIV-) individuals. We conducted a...
Comparison of the predictive performance of adherence measures for virologic failure detection in people living with HIV: A systematic review and pairwise meta-analysis
A critical feature of an adherence assessment tool is its ability to predict virologic failure in people living with HIV (PLHIV). We, therefore, aimed to compare the predictive performance of...
Effectiveness of ombitasvir/paritaprevir/ritonavir, dasabuvir for HCV in HIV/HCV coinfected subjects: A comprehensive analysis
BACKGROUND: Data on the treatment of patients with hepatitis C virus (HCV)/human immunodeficiency virus (HIV) coinfection remains limited. A comprehensive analysis was performed to evaluate the efficacy and safety of...
Content guidance for mobile phones short message service (SMS)-based antiretroviral therapy adherence and appointment reminders: A review of the literature
Mobile phones are increasingly being used to support health activities, including the care and management of people living with HIV/AIDS. Short message service (SMS) has been explored as a means...
Epidemiology of depressive disorders in people living with HIV in Africa: A systematic review and meta-analysis: Burden of depression in HIV in Africa
OBJECTIVE: The burden of HIV infection is higher in Africa where 70% of people living with HIV (PLHIV) resides. Since depression can negatively impact the course of HIV infection, it...
Unintended pregnancy in women living with HIV in sub-Saharan Africa: A systematic review and meta-analysis
In 2014, about 1.5 million pregnancies occurred among HIV-positive women in low and middle-income countries. To pool magnitude and factors associated with unintended pregnancy in women living with HIV in...
Attrition of HIV-exposed infants from early infant diagnosis services in low- and middle-income countries: A systematic review and meta-analysis
INTRODUCTION: Identification and retention of HIV-exposed infants in early infant diagnosis (EID) services helps to ensure optimal health outcomes. This systematic review and meta-analysis examines the magnitude of attrition from...
Physical activity and HIV in sub-Saharan Africa: A systematic review of correlates and levels
Background: Self-management strategies such as physical activity (PA) can address disability and optimize mental, physical, social and economic outcomes for persons living with HIV (PLWH). Understanding factors that influence PA...
Risk of sexual transmission of human immunodeficiency virus with antiretroviral therapy, suppressed viral load and condom use: A systematic review
BACKGROUND: The Public Health Agency of Canada reviewed sexual transmission of HIV between serodiscordant partners to support examination of the criminal justice system response to HIV nondisclosure by the Department...
The effect of demand-side financial incentives for increasing linkage into HIV treatment and voluntary medical male circumcision: A systematic review and meta-analysis of randomised controlled trials in low- and middle-income countries
INTRODUCTION: Linkage to HIV treatment is a vital step in the cascade of HIV services and is critical to slowing down HIV transmission in countries with high HIV prevalence. Equally,...
Socio-structural factors influencing the prevention of mother-to-child transmission of HIV in the democratic republic of the Congo: A systematic review
Introduction The Democratic Republic of the Congo (DRC) had the second-highest mother-to-child HIV transmission rate in Sub-Saharan Africa at 29% in 2013, however the uptake of preventive services for mother-to-child...
