Category Archives: Engagement and Care Cascade
Efficacy and safety of raltegravir-based dual therapy in AIDS patients: A meta-analysis of randomized controlled trials
Background: The life expectancy for HIV-infected individuals has improved dramatically because of improvements in antiretroviral therapy (ART). Today, a simplified two-drug regimen enhances adherence and treatment satisfaction by reducing adverse...
HIV viral resuppression following an elevated viral load: A systematic review and meta-analysis
INTRODUCTION: Guidelines for antiretroviral therapy recommend enhanced adherence counselling be provided to individuals with an initial elevated viral load before making a decision whether to switch antiretroviral regimen. We undertook...
Male participation in reproductive health interventions in sub-Saharan Africa: A scoping review
CONTEXT: Despite improvements in reproductive health indicators among women living in Sub-Saharan Africa, the persistence of poor outcomes underscores the need to examine recent interventions to inform future research, programming...
Trend of HIV-1 drug resistance in China: A systematic review and meta-analysis of data accumulated over 17 years (2001-2017)
Background: The emergence and spread of HIV-1 drug resistance may compromise HIV control globally. In response to HIV/AIDS epidemic, China launched national HIV/AIDS treatment program in 2003, and started to...
Treatment failure and associated factors among first line patients on highly active antiretroviral therapy in Ethiopia: A systematic review and meta-analysis
Background: Antiretroviral therapy (ART) restores immune function and reduces human immunodeficiency virus (HIV) related adverse outcomes. The results of previous studies in Ethiopia were replete with inconsistent findings; nonexistence of...
Crowdsourcing methods to enhance HIV and sexual health services: A scoping review and qualitative synthesis
BACKGROUND: Crowdsourcing is increasingly used to improve community engagement in HIV and sexual health research. In this scoping review, we reviewed studies using crowdsourcing approaches in HIV and sexual health...
Immunological and virological responses in older HIV-infected adults receiving antiretroviral therapy: An evidence-based meta-analysis
Millions of people living with the human immunodeficiency virus (HIV) have received antiretroviral therapy (ART). Older adults make up a significant portion of these individuals, however, the immunological and virological...
Social and structural determinants of HIV treatment and care among Hispanic women and Latinas living with HIV infection in the United States: A qualitative review: 2008-2018
Purpose: In 2017, among all women in the United States, Hispanic women and Latinas (Hispanics/Latinas) accounted for 16% of women with HIV. Populations with high HIV disparities, including Hispanics/Latinas, experience...
Child-centred care in HIV service provision for children in resource constrained settings: A narrative review of literature
Introduction: Child-centred care approaches are increasingly gaining traction in healthcare; and are being applied in the delivery of HIV care for children in resource constrained settings. However, very little is...
A client-centered relational framework on barriers to the integration of HIV and substance use services: A systematic review
BACKGROUND: Given the close connection between human immunodeficiency virus (HIV) infection and substance use disorder (SUD), access to integrated HIV and SUD services is critical for individuals experiencing both challenges...
Magnitude and causes of first-line antiretroviral therapy regimen changes among HIV patients in Ethiopia: A systematic review and meta-analysis
BACKGROUND: Antiretroviral therapy (ART) has markedly decreased the morbidity and mortality due to HIV/AIDS. ART regimen change is a major challenge for the sustainability of human immunodeficiency virus (HIV) treatment...
