Category Archives: Engagement and Care Cascade

Are policy initiatives aligned to meet UNAIDS 90-90-90 targets impacting HIV testing and linkages to care? Evidence from a systematic review

2019

Background: The Joint United Nations Programme on HIV/AIDS (UNAIDS) Fast-Track initiative seeks to eliminate AIDS as a health threat by 2030, with its focus on UNAIDS 90-90-90 targets. Effective policies and...

Which community-based HIV initiatives are effective in achieving UNAIDS 90-90-90 targets? A systematic review and meta-analysis of evidence (2007-2018)

2019

BACKGROUND: Reaching the Joint United Nations Programme on HIV/AIDS (UNAIDS) 90-90-90 targets to end the HIV epidemic relies on effective interventions that engage untested HIV+ individuals and retain them in...

Out-of-pocket costs associated with HIV in publicly funded high-income health care settings

2019

Key take-home messages The aging of the people living with HIV in care is leading to increased HIV care costs. There is considerable inter-jurisdictional heterogeneity in the cost-sharing policies for...

Associations between human leukocyte antigen polymorphisms and hypersensitivity to antiretroviral therapy in patients with human immunodeficiency virus: A meta-analysis

2019

Background Human leukocyte antigen (HLA) alleles are implicated in drug-induced hypersensitivity, including by nevirapine and abacavir. The purpose of this meta-analysis was to evaluate the relationship between HLA polymorphisms and...

Strategies to link people with undiagnosed HIV infection to HIV testing, care, and prevention services

2019

Key take-home messages A variety of strategies have shown promise for identifying individuals with undiagnosed HIV and engaging them with HIV testing using clinical, community-based, network-based, and self-directed approaches. Various...

Performance of cepheid GeneXpert HIV-1 viral load plasma assay to accurately detect treatment failure: A clinical meta-analysis

2019

BACKGROUND: Coverage of viral load testing remains low with only half of the patients in need having adequate access. Alternative technologies to high throughput centralized machines can be used to...

A comparative review of mobile health and electronic health utilization in sub-Saharan African countries

2019

This study distinguished between the application of e-health and m-health technologies in sub-Saharan African (SSA) countries based on the dimensions of use, targeted diseases or health conditions, locations of use,...

Health literacy and health outcomes in persons living with HIV disease: A systematic review

2019

Low health literacy is associated with challenges for those living with HIV including medication non-adherence and poorer health outcomes. The aim of this study was to systematically review the literature...

HIV-related care for transgender people: A systematic review of studies from around the world

2019

RATIONALE: Transgender people face unique challenges, such as structural, interpersonal, and individual vulnerabilities to chronic diseases. Stigma and prejudice may hamper their access to health care and prevent their inclusion...

Is co-location of services with HIV care associated with improved HIV care outcomes? A systematic review

2019

This systematic review identifies models of service co-location, a structural intervention strategy to remove barriers to HIV care and services, and examines their associations with HIV care outcomes. A cumulative...

A systematic mixed studies review of the intersections of social-ecological factors and HIV stigma in people living with HIV in the U.S. south

2019

The role of stigma on psychological wellness and treatment outcomes in people living with HIV (PLWH) has been well documented. However, within the context of the southern United States, the...

Managing pharmacotherapy in people living with HIV and concomitant malignancy

2019

OBJECTIVE: To describe data with selected malignancies in people living with HIV (PLWH) and HIV in individuals affected by both conditions and to summarize drug-drug interactions (DDIs) with clinical recommendations...

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