Category Archives: Engagement and Care Cascade
Progressive disseminated histoplasmosis in Latin America and the Caribbean in people receiving highly active antiretroviral therapy for HIV infection: A systematic review
Histoplasmosis is the most clinically significant mycosis in Latin America; still it has been neglected in people with human immunodeficiency virus (HIV). There is limited information about its contribution to...
Assessment of country policies affecting reproductive health for adolescents in the Philippines
BACKGROUND: Adolescents in the Philippines face many legal, social and political barriers to access sexual and reproductive health (SRH) services, putting them at higher risk of unplanned pregnancy, abortion, sexually...
Associations between anxiety and adherence to antiretroviral medications in low- and middle-income countries: A systematic review and meta-analysis
Untreated mental health disorders among people living with HIV (PLHIV) may prevent low- and middle-income countries (LMICs) from achieving the UNAIDS 90-90-90 targets. Anxiety disorders may be associated with decreased...
Older African Americans and the HIV care continuum: A systematic review of the literature, 2003-2018
Evidence suggests that racial disparities in the HIV care continuum persist in older age groups, particularly among African Americans. The objective of this systematic review was to identify factors that...
Attrition of HIV-exposed infants from early infant diagnosis services in low- and middle-income countries: A systematic review and meta-analysis
INTRODUCTION: Identification and retention of HIV-exposed infants in early infant diagnosis (EID) services helps to ensure optimal health outcomes. This systematic review and meta-analysis examines the magnitude of attrition from...
HIV, depression, and cognitive impairment in the era of effective antiretroviral therapy
PURPOSE OF REVIEW: Mental health disorders, especially depression, are prevalent among people living with HIV (PLWH) and are associated with cognitive impairment (CI) among HIV-uninfected (HIV-) individuals. We conducted a...
Comparison of the predictive performance of adherence measures for virologic failure detection in people living with HIV: A systematic review and pairwise meta-analysis
A critical feature of an adherence assessment tool is its ability to predict virologic failure in people living with HIV (PLHIV). We, therefore, aimed to compare the predictive performance of...
The effect of demand-side financial incentives for increasing linkage into HIV treatment and voluntary medical male circumcision: A systematic review and meta-analysis of randomised controlled trials in low- and middle-income countries
INTRODUCTION: Linkage to HIV treatment is a vital step in the cascade of HIV services and is critical to slowing down HIV transmission in countries with high HIV prevalence. Equally,...
Socio-structural factors influencing the prevention of mother-to-child transmission of HIV in the democratic republic of the Congo: A systematic review
Introduction The Democratic Republic of the Congo (DRC) had the second-highest mother-to-child HIV transmission rate in Sub-Saharan Africa at 29% in 2013, however the uptake of preventive services for mother-to-child...
Effectiveness of ombitasvir/paritaprevir/ritonavir, dasabuvir for HCV in HIV/HCV coinfected subjects: A comprehensive analysis
BACKGROUND: Data on the treatment of patients with hepatitis C virus (HCV)/human immunodeficiency virus (HIV) coinfection remains limited. A comprehensive analysis was performed to evaluate the efficacy and safety of...
Content guidance for mobile phones short message service (SMS)-based antiretroviral therapy adherence and appointment reminders: A review of the literature
Mobile phones are increasingly being used to support health activities, including the care and management of people living with HIV/AIDS. Short message service (SMS) has been explored as a means...
Screening for HIV and linkage to care in adolescents: Insights from a systematic review of recent interventions in high- versus low- and middle-income settings
Introduction: Compared to adults, adolescents and young adults have a higher incidence of HIV infection, yet lower rates of HIV testing. Few evidence-based interventions effectively diagnose new HIV infections among...
