Category Archives: Prevention, Engagement and Care Cascade
Rapid evidence review of harm reduction interventions and messaging for people who inject drugs during pandemic events: Implications for the ongoing COVID-19 response
BACKGROUND: People who inject drugs are at increased health risk in a pandemic due to their greater susceptibility to severe disease and as a consequence of the restrictions put in...
Psychosocial support interventions for improved adherence and retention in ART care for young people living with HIV (10-24 years): A scoping review
Background: Mental health disorders such as high levels of anxiety, isolation, depression and suicide ideation reported among young people living with HIV (10-24 years;YPLHIV) contribute significantly to poor medication adherence...
Interactive digital interventions for prevention of sexually transmitted HIV: Systematic review and meta-analyses
BACKGROUND: Digital technology offers good opportunities for HIV prevention. This systematic review assesses the effectiveness of interactive digital interventions (IDIs) for prevention of sexually transmitted HIV. METHODS: We conducted a...
Interventions to improve daily medication use among adolescents and young adults: What can we learn for youth pre-exposure prophylaxis services?
OBJECTIVE: Oral pre-exposure prophylaxis (PrEP) is an important HIV prevention method and studies have shown that young people ages 15-24 have difficulty adhering to daily PrEP. The field of PrEP...
Retention in care and viral suppression in differentiated service delivery models for HIV treatment delivery in sub-Saharan Africa: A rapid systematic review
INTRODUCTION: Differentiated service delivery (DSD) models for antiretroviral treatment (ART) for HIV are being scaled up in the expectation that they will better meet the needs of patients, improve the...
The magnitude of adherence to option B plus program and associated factors among women in eastern African countries: A systematic review and meta-analysis
Background: Despite coverage and benefits associated with the prevention of mothers to child transmission (PMTCT) services, mothers’ adherence to option B plus is still a challenge. Though few primary studies...
What do we know about patient-provider interactions in sub-Saharan Africa? A scoping review
INTRODUCTION: patient-centred care has become a rallying call for improving quality and access to care in countries where health system responsiveness and satisfaction with health services remain low. Understanding patient-provider...
Barriers preventing access by men who have sex with men to HIV-related health services in Southeast Asia: A scoping review
The objective of this scoping review was to identify and describe barriers experienced by men who have sex with men (MSM) when accessing HIV-related health care in Southeast Asia. A...
Factors associated with antiretroviral treatment failure among people living with HIV on antiretroviral therapy in resource-poor settings: A systematic review and metaanalysis
BACKGROUND: Despite the increase in the number of people accessing antiretroviral therapy (ART), there is limited data regarding treatment failure and its related factors among HIV-positive individuals enrolled in HIV...
Immunogenicity of pneumococcal vaccination in HIV infected individuals: A systematic review and meta-analysis
Background: The objective of this systematic review and meta-analysis was to summarise the literature regarding the immunogenicity of pneumococcal conjugate vaccines (PCV) and pneumococcal polysaccharide vaccines (PPSV) in adult people...
Comparative efficacy, tolerability and safety of dolutegravir and efavirenz 400mg among antiretroviral therapies for first-line HIV treatment: A systematic literature review and network meta-analysis
Background: To inform World Health Organization (WHO) global guidelines, we updated and expanded the evidence base to assess the comparative efficacy, tolerability, and safety of first-line antiretroviral therapy (ART) regimens....
