Category Archives: Prevention, Engagement and Care Cascade
Youth engagement in HIV prevention intervention research in sub-Saharan Africa: A scoping review
INTRODUCTION: Youth engagement in HIV research is generally recognized as essential, but often neglected or minimally implemented in practice. Engagement is a process of working collaboratively with diverse groups of...
The impact of antiretroviral therapy on neurocognitive outcomes among people living with HIV in low- and middle-income countries (LMICs): A systematic review
Low and middle-income countries (LMICs) are the epicenter of the HIV epidemic. The scale-up of antiretroviral therapy (ART) has reduced mortality, but HIV-associated neurocognitive impairment (HANI) remains prevalent, which impacts...
The level of unmet need for family planning and its predictors among HIV-positive women in Ethiopia: A systematic review and meta-analysis
BACKGROUND: Studies indicated that the need for family planning appears to be greater for human immuno-deficiency virus- (HIV-) positive women than the general population to reduce the risk of pediatrics...
Evidence regarding rapid initiation of antiretroviral therapy in patients living with HIV
PURPOSE OF REVIEW: Rapid initiation of antiretroviral therapy (ART) is increasingly more common among clinics serving people living with human immunodeficiency virus (PLWH). It is recommended by major guidelines and...
Growth in proportion and disparities of HIV PrEP use among key populations identified in the United States national goals: Systematic review and meta-analysis of published surveys
BACKGROUND: Pre-exposure prophylaxis (PrEP) use among populations most vulnerable to HIV as identified in the national HIV prevention goals is not fully known. This systematic review assessed trends of lifetime...
Risk factors for loss to follow-up from antiretroviral therapy programmes in low-income and middle-income countries
Introduction: Loss to follow-up (LTFU) rates from antiretroviral treatment (ART) programmes in low- and middle-income countries (LMIC) are high, leading to poor treatment outcomes and onward transmission of HIV. Knowledge of...
Global burden of active smoking among people living with HIV on antiretroviral therapy: A systematic review and meta-analysis
Background: Although the high burden of both active smoking and human immunodeficiency virus (HIV) is clearly known, the relationship between them is still not well characterized. Therefore, we estimated the...
Impact of advanced HIV disease on quality of life and mortality in the era of combined antiretroviral treatment
Currently, AIDS or severe immunodeficiency remains as a challenge for people with HIV (PWHIV) and healthcare providers. Our purpose was to analyze the impact of advanced HIV disease (AHD) on...
A mega-aggregation framework synthesis of the barriers and facilitators to linkage, adherence to ART and retention in care among people living with HIV
BACKGROUND: People living with human immunodeficiency virus (PLHIV) struggle with the challenges of living with a chronic disease and integrating antiretroviral treatment (ART) and care into their daily lives. The...
Efficacy of psychological interventions towards the reduction of high-risk sexual behaviors among people living with HIV: A systematic review and meta-analysis, 2010-2020
People living with HIV/AIDS (PLWH) may be vulnerable to mental illness. As sexual transmission is the leading cause of HIV infection, evidence-based study for the effect of psychological interventions on...
Barriers and facilitators to pre-exposure prophylaxis among African migrants in high income countries: A systematic review
BACKGROUND: The aim of this review is to explore acceptability, barriers, and facilitators to PrEP use among African migrants in high-income countries. METHODS: A systematic review was conducted to explore...
