Category Archives: Prevention, Engagement and Care Cascade

Efficacy and safety of triple versus dolutegravir-based dual therapy in patients with HIV-1 infection: A meta-analysis of randomized controlled trials

2021

A new strategy of simplification therapy shown the unique benefits in clinical treatment, by reducing pill burden and avoid drug exposure. To provide more evidence for the strategy, we compared...

Significance of the placental barrier in antenatal viral infections

2021

The placenta provides a significant physical and physiological barrier to prevent fetal infection during pregnancy. Nevertheless, it is at times breached by pathogens and leads to vertical transmission of infection...

Important role of microglia in HIV-1 associated neurocognitive disorders and the molecular pathways implicated in its pathogenesis

2021

The development of effective combined anti-retroviral therapy (cART) led to a significant reduction in the death rate associated with human immunodeficiency virus type 1 (HIV-1) infection. However, recent studies indicate...

Long-acting reversible contraception, condom use, and sexually transmitted infections: A systematic review and meta-analysis

2021

Introduction Given mixed findings regarding the relationship between long-acting reversible contraception and condom use, this systematic review and meta-analysis synthesizes studies comparing sexually transmitted infection‒related outcomes between users of long-acting...

Academic detailing to increase prescribing of HIV pre-exposure prophylaxis

2021

Although HIV pre-exposure prophylaxis can decrease new cases of HIV by up to 99%, many patients who could benefit from pre-exposure prophylaxis never receive prescriptions for it. Because pre-exposure prophylaxis...

Gut microbiome in people living with HIV is associated with impaired thiamine and folate syntheses

2021

People living with HIV have a high incidence of cardiovascular and neurological diseases as comorbid disorders that are commonly linked to inflammation. While microbial translocation can augment inflammation during HIV...

Global prevalence and associated risk factors of diarrheagenic Giardia duodenalis in HIV/AIDS patients: A systematic review and meta-analysis

2021

Giardia duodenalis is one of the leading causes of diarrhea, mostly in underdeveloped nations of Africa and Asia. The present review provides insights into the prevalence, odds ratios (ORs) and...

Hepatotoxicity of contemporary antiretroviral drugs

2021

PURPOSE OF REVIEW: To date, more than 30 antiretroviral drugs have been approved by the Food and Drug Administration for the treatment of HIV infection. As new drugs with better...

mHealth in the prevention of sexually transmitted infections STIs

2020

The objective of this study was to analyze in the literature how the applications were developed and how they influence the prevention of Sexually Transmitted Infections (STIs). PubMed, CAPES Periodicals...

Effectiveness of and best practices for using contingency management and incentives for health care issues related to HIV, sexually transmitted infections (STIs), and pre-exposure prophylaxis (PrEP)

2021

Using contingency management and incentives at the different steps of HIV care continuum (such as testing, treatment adherence, viral suppressions) is widely explored and discussed in the literature, whereas the...

Factors associated with methamphetamine use among men who have sex with men

2021

An abundance of literature details problematic sexualized drug use among men who have sex with men; additionally, several interventions attempt to address methamphetamine dependence in this population. Several factors are...

Immediate initiation of antiretroviral therapy (ART) after HIV diagnosis

2021

The benefits of beginning antiretroviral therapy (ART) soon after HIV diagnosis include improved health outcomes across a wide variety of settings as well as decreased long term healthcare costs. Generally,...

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