Category Archives: Prevention, Engagement and Care Cascade
Evidence regarding rapid initiation of antiretroviral therapy in patients living with HIV
PURPOSE OF REVIEW: Rapid initiation of antiretroviral therapy (ART) is increasingly more common among clinics serving people living with human immunodeficiency virus (PLWH). It is recommended by major guidelines and...
Growth in proportion and disparities of HIV PrEP use among key populations identified in the United States national goals: Systematic review and meta-analysis of published surveys
BACKGROUND: Pre-exposure prophylaxis (PrEP) use among populations most vulnerable to HIV as identified in the national HIV prevention goals is not fully known. This systematic review assessed trends of lifetime...
Risk factors for loss to follow-up from antiretroviral therapy programmes in low-income and middle-income countries
Introduction: Loss to follow-up (LTFU) rates from antiretroviral treatment (ART) programmes in low- and middle-income countries (LMIC) are high, leading to poor treatment outcomes and onward transmission of HIV. Knowledge of...
Strategies for retention of heterosexual men in HIV care in sub-Saharan Africa: A systematic review
Expansion of Antiretroviral Therapy (ART) programs in sub-Saharan Africa (SSA) has increased the number of people accessing treatment. However, the number of males accessing and being retained along the human...
Structural interventions for HIV prevention and care among US men who have sex with men: A systematic review of evidence, gaps, and future priorities
The preponderance of HIV interventions have been behavioral, targeting individual, dyadic, or group dynamics. However, structural-level interventions are required to decrease HIV transmission and increase engagement in care, especially for...
Effectiveness and safety of dolutegravir two-drug regimens in virologically suppressed people living with HIV: A systematic literature review and meta-analysis of real-world evidence
Objectives: Dolutegravir (DTG) is widely recommended within three-drug regimens. However, similar efficacy and tolerability have also been achieved with DTG within two-drug regimens in clinical trials. This study evaluated the real-world...
A systematic review of early adoption of implementation science for HIV prevention or treatment in the United States
OBJECTIVE: To provide the first systematic review of the early adoption of implementation science for HIV prevention or treatment in the United States. We identified primary research studies that addressed...
Missed opportunities for sexually transmitted infections testing for HIV pre-exposure prophylaxis users: A systematic review
Introduction: Given the synergistic relationship between HIV and sexually transmitted infections (STI), the integration of services has the potential to reduce the incidence of both HIV and STIs. We explored the...
Barriers and facilitators to pre-exposure prophylaxis among African migrants in high income countries: A systematic review
BACKGROUND: The aim of this review is to explore acceptability, barriers, and facilitators to PrEP use among African migrants in high-income countries. METHODS: A systematic review was conducted to explore...
HIV self-testing uptake and intervention strategies among men in Sub-Saharan Africa: A systematic review
Background: HIV testing is an essential gateway to HIV prevention and treatment services. However, HIV testing uptake remains low among men due to stigma, discrimination, and confidentiality concerns. HIV self-testing...
