Category Archives: Prevention, Engagement and Care Cascade

Impact of male circumcision on risk of HIV infection in men in a changing epidemic context — Systematic review and meta-analysis

2020

INTRODUCTION: WHO/UNAIDS recommended Voluntary Medical Male Circumcision in 2007 based on systematic review of observational studies prior to 1999 and three randomized controlled trials (RCTs). To inform updated WHO guidance,...

Oral pre-exposure prophylaxis (PrEP) continuation, measurement, and reporting: A systematic review and meta-analysis

2020

OBJECTIVE: To appropriately plan for rollout and monitor impact of oral pre-exposure prophylaxis (PrEP) it is important to understand PrEP continuation and come to a consensus on how best to...

Human immunodeficiency virus positive status disclosure to a sexual partner and its determinant factors in Ethiopia: A systematic review and meta-analysis

2020

BACKGROUND: Disclosure of Human Immunodeficiency Virus positive status significantly reduced the transmission of HIV; yet, it remains a challenge for many HIV patients. Disclosure serves plays a crucial role to...

A systematic review of HIV interventions for young women in sub-Saharan Africa

2020

Adolescent girls and young women (AGYW) ages (15-24 years old) in Southern and Eastern Africa account for nearly 30% of all new HIV infections. We conducted a systematic review of...

A systematic review of recent methodological approaches for using ecological momentary assessment to examine outcomes in U.S. based HIV research

2020

PURPOSE OF REVIEW: In recent years, researchers have been adopting and using ecological momentary assessment (EMA) methods via technology devices for real-time measurement of exposures and outcomes in HIV research....

HIV/AIDS-knowledge and attitudes in the Arabian Peninsula: A systematic review and meta-analysis

2020

BACKGROUND: HIV/AIDS prevention has been widely adopted worldwide, but little is known about HIV/AIDS knowledge and attitudes in the Arabian Peninsula. AIM: To summarize the level of knowledge and attitude...

A realist systematic review of stigma reduction interventions for HIV prevention and care continuum outcomes among men who have sex with men

2020

While stigma associated with human immunodeficiency virus (HIV) infection among men who have sex with men (MSM) is well recognized, there remains relatively limited intervention data on effective stigma reduction...

A review of usability evaluation methods and their use for testing eHealth HIV interventions

2020

PURPOSE OF REVIEW: To provide a comprehensive review of usability testing of eHealth interventions for HIV. RECENT FINDINGS: We identified 28 articles that assessed the usability of eHealth interventions for...

A systematic review and meta-analysis of interventions for orphans and vulnerable children affected by HIV/AIDS worldwide

2020

BACKGROUND: Worldwide, there are more than 13.3 million orphans and vulnerable children affected by Human immunodeficiency virus infection and acquired immune deficiency syndrome (HIV/AIDS) (HIV OVC), defined as individuals below...

Effect of omega-3 polyunsaturated fatty acids treatment on lipid pattern of HIV patients: A meta-analysis of randomized clinical trials

2020

Even though omega-3 polyunsaturated fatty acids (PUFAs) seem to be effective in the treatment of human immunodeficiency virus (HIV)-associated dyslipidemia, their impact is still debated. For this reason, our aim...

Direct-acting antivirals for HCV treatment in older patients: A systematic review and meta-analysis

2020

The advent of highly effective and well-tolerated direct antiviral antivirals (DAAs) has dramatically changed the landscape of chronic hepatitis C. The effect of DAAs in older adults is difficult to...

The pharmacogenetics of efavirenz metabolism in children: The potential genetic and medical contributions to child development in the context of long-term ARV treatment

2020

Efavirenz (EFV) is a well-known, effective anti-retroviral drug long used in first-line treatment for children and adults with HIV and HIV/AIDS. Due to its narrow window of effective concentrations, between...

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