Category Archives: Prevention, Engagement and Care Cascade

Meta-analysis of TB & HIV co-infection mortality rate in sub-Saharan African children, youth, and adolescents

2025

Background Despite the effectiveness of antiretroviral treatment (ART) in reducing morbidity and mortality, children and adolescents with co-infections face an elevated risk of death due to their young age and...

Undetectable = Untransmittable: A cross-population systematic review and meta-analysis on awareness and acceptance

2025

The Undetectable = Untransmittable (U=U) message is a cornerstone of HIV-related public health communication, yet global levels of awareness and acceptance remain unclear across key populations. This study aimed to...

Manifestation and markings of HIV stigma in Indonesia: A scoping review

2025

Stigma related to HIV hinders access to healthcare services and worsens the quality of life for people living with HIV (PLHIV). A comprehensive understanding of HIV stigma is crucial for...

Retention in HIV care among Southeast Asian people living with HIV: A systematic review and meta-analysis

2025

Background Despite the effectiveness of antiretroviral therapy (ART) in reducing HIV-related morbidity and mortality, the retention of HIV care remains suboptimal in Southeast Asia. Objective This systematic review and meta-analysis...

Evaluating predictive performance, validity, and applicability of machine learning models for predicting HIV treatment interruption: A systematic review

2025

Background HIV treatment interruption remains a significant barrier to achieving global HIV/AIDS control goals. Machine learning (ML) models offer potential for predicting treatment interruption by leveraging large clinical data. Understanding...

Immune responses to vaginal candidiasis in African women: A scoping review of cytokine profiles, T-cell activation, and gene expression

2025

Background Recent immunological studies of vaginal candidiasis in African populations have revealed complex host‒pathogen interactions with implications for therapeutic development and HIV acquisition risk. Objective This scoping review synthesized evidence...

Adolescents’ sexual health during the COVID-19 outbreak: A systematic review

2025

BACKGROUND AND AIMS: The COVID-19 pandemic has greatly disrupted adolescents’ access to sexual health services, resulting in a decline in their overall sexual well-being. This systematic review explored adolescent sexual...

Doxycycline prophylaxis for the prevention of bacterial sexually transmitted infections (STIs): doxyPrEP and doxyPEP

2024

No abstract available

Social and structural determinants of health influencing HIV risk and participation across the HIV care cascade

2025

Key take-home messages

Transitioning to adult HIV care: Challenges and evidence-based practices

2025

Key take-home messages

Pneumocystis infection in pregnant women: A scoping review

2025

Pneumocystis jirovecii is an opportunistic fungus that causes severe pneumonia in immunosuppressed individuals. While Pneumocystis colonization, a subclinical form of infection, has been studied in different populations, its implications during...

Family influences on antiretroviral therapy adherence in youth with HIV in the United States: A systematic review

2025

HIV poses a significant issue in the United States and understanding how HIV-positive populations adhere to treatments, specifically with antiretroviral therapy (ART), is vital for researchers to find approaches to...

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